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Silvia Portugal

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Articles 43
Citations 2227
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Recent Articles
1.
Figueiredo A, Rastogi S, Ramos S, Nogueira F, De Villiers K, de Sousa A, et al.
bioRxiv . 2025 Mar; PMID: 40060532
Whether jaundice, a common presentation of ( .) malaria (1-3) arising from the accumulation of circulating bilirubin, represents an adaptive or maladaptive response to spp. infection is not understood (1-3)....
2.
Wunderlich J, Kotov V, Votborg-Novel L, Ntalla C, Geffken M, Peine S, et al.
Front Cell Infect Microbiol . 2024 Nov; 14:1480076. PMID: 39575308
Host iron deficiency is protective against severe malaria as the human malaria parasite depends on bioavailable iron from its host to proliferate. The essential pathways of iron acquisition, storage, export,...
3.
Andrade C, Carrasquilla M, Dabbas U, Briggs J, van Dijk H, Sergeev N, et al.
EMBO Mol Med . 2024 Sep; 16(10):2349-2375. PMID: 39284949
Persistence of malaria parasites in asymptomatic hosts is crucial in areas of seasonally-interrupted transmission, where P. falciparum bridges wet seasons months apart. During the dry season, infected erythrocytes exhibit extended...
4.
Kayentao K, Ongoiba A, Preston A, Healy S, Hu Z, Skinner J, et al.
N Engl J Med . 2024 Apr; 390(17):1549-1559. PMID: 38669354
Background: Subcutaneous administration of the monoclonal antibody L9LS protected adults against controlled infection in a phase 1 trial. Whether a monoclonal antibody administered subcutaneously can protect children from infection in...
5.
de Cesare M, Mwenda M, Jeffreys A, Chirwa J, Drakeley C, Schneider K, et al.
Nat Commun . 2024 Feb; 15(1):1413. PMID: 38360754
Genomic surveillance of Plasmodium falciparum malaria can provide policy-relevant information about antimalarial drug resistance, diagnostic test failure, and the evolution of vaccine targets. Yet the large and low complexity genome...
6.
Stadler E, Cromer D, Ogunlade S, Ongoiba A, Doumbo S, Kayentao K, et al.
Malar J . 2023 Feb; 22(1):42. PMID: 36737743
Background: In malaria endemic regions, transmission of Plasmodium falciparum parasites is often seasonal with very low transmission during the dry season and high transmission in the wet season. Parasites survive...
7.
Thomson-Luque R, Votborg-Novel L, Osorio N, Portugal S
Nat Commun . 2022 Sep; 13(1):5558. PMID: 36151088
No abstract available.
8.
Andrade C, Fleckenstein H, Thomson-Luque R, Doumbo S, Lima N, Anderson C, et al.
Nat Med . 2022 Aug; 28(10):2216. PMID: 35927582
No abstract available.
9.
LaVerriere E, Schwabl P, Carrasquilla M, Taylor A, Johnson Z, Shieh M, et al.
Mol Ecol Resour . 2022 Apr; 22(6):2285-2303. PMID: 35437908
Multiplexed PCR amplicon sequencing (AmpSeq) is an increasingly popular application for cost-effective monitoring of threatened species and managed wildlife populations, and shows strong potential for the genomic epidemiology of infectious...
10.
Portugal S, Rodriguez A, Prudencio M
Front Cell Infect Microbiol . 2022 Feb; 12:851484. PMID: 35211424
No abstract available.