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Silvia Kocanova

Explore the profile of Silvia Kocanova including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 337
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Recent Articles
1.
Platania A, Erb C, Barbieri M, Molcrette B, Grandgirard E, de Kort M, et al.
Sci Adv . 2024 Dec; 10(50):eadq0987. PMID: 39671497
The spatiotemporal configuration of genes with distal regulatory elements is believed to be crucial for transcriptional control, but full mechanistic understanding is lacking. We combine simultaneous live tracking of pairs...
2.
Kocanova S, Raynal F, Goiffon I, Oksuz B, Bau D, Kamgoue A, et al.
Life Sci Alliance . 2023 Nov; 7(2). PMID: 37989525
The genome is organized in functional compartments and structural domains at the sub-megabase scale. How within these domains interactions between numerous cis-acting enhancers and promoters regulate transcription remains an open...
3.
Sexton T, Platania A, Erb C, Barbieri M, Molcrette B, Grandgirard E, et al.
Res Sq . 2023 Aug; PMID: 37645793
The spatiotemporal configuration of genes with distal regulatory elements, and the impact of chromatin mobility on transcription, remain unclear. Loop extrusion is an attractive model for bringing genetic elements together,...
4.
Platania A, Erb C, Barbieri M, Molcrette B, Grandgirard E, de Kort M, et al.
bioRxiv . 2023 May; PMID: 37162887
The spatiotemporal configuration of genes with distal regulatory elements, and the impact of chromatin mobility on transcription, remain unclear. Loop extrusion is an attractive model for bringing genetic elements together,...
5.
Mompart F, Kamgoue A, Lahbib-Mansais Y, Robelin D, Bonnet A, Rogel-Gaillard C, et al.
BMC Mol Cell Biol . 2021 Sep; 22(1):45. PMID: 34521351
Background: The crucial role of the major histocompatibility complex (MHC) for the immune response to infectious diseases is well-known, but no information is available on the 3D nuclear organization of...
6.
Germier T, Audibert S, Kocanova S, Lane D, Bystricky K
Methods . 2018 Apr; 142:16-23. PMID: 29660486
Spatio-temporal organization of the cell nucleus adapts to and regulates genomic processes. Microscopy approaches that enable direct monitoring of specific chromatin sites in single cells and in real time are...
7.
Kocanova S, Goiffon I, Bystricky K
Methods . 2018 Mar; 142:3-15. PMID: 29501423
Fluorescence in situ hybridization (FISH) is a common technique used to label DNA and/or RNA for detection of a genomic region of interest. However, the technique can be challenging, in...
8.
Germier T, Kocanova S, Walther N, Bancaud A, Shaban H, Sellou H, et al.
Biophys J . 2017 Oct; 113(7):1383-1394. PMID: 28978433
Genome dynamics are intimately linked to the regulation of gene expression, the most fundamental mechanism in biology, yet we still do not know whether the very process of transcription drives...
9.
Bayindir I, Babaeikelishomi R, Kocanova S, Sousa I, Lerch S, Hardt O, et al.
Front Endocrinol (Lausanne) . 2015 Sep; 6:129. PMID: 26347713
De novo formation of beige/brite adipocytes from progenitor cells contributes to the thermogenic adaptation of adipose tissue and holds great potential for the therapeutic remodeling of fat as a treatment...
10.
Lavigne A, Castells M, Mermet J, Kocanova S, Dalvai M, Bystricky K
PLoS One . 2014 Jun; 9(6):e98930. PMID: 24911873
Purpose: Epithelial-Mesenchymal Transition (EMT) features appear to be key events in development and progression of breast cancer. Epigenetic modifications contribute to the establishment and maintenance of cancer subclasses, as well...