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Silvestra Barrena-Blazquez

Explore the profile of Silvestra Barrena-Blazquez including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 64
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Recent Articles
1.
Ortega M, Boaru D, De Leon-Oliva D, De Castro-Martinez P, Minaya-Bravo A, Casanova-Martin C, et al.
Genes (Basel) . 2025 Feb; 16(2). PMID: 40004457
Klotho, initially identified as an anti-aging gene, has been shown to play significant roles in cancer biology. Alongside α-Klotho, the β-Klotho and γ-Klotho isoforms have also been studied; these studies...
2.
Fraile-Martinez O, Garcia-Montero C, Gomez-Lahoz A, Sainz F, Bujan J, Barrena-Blazquez S, et al.
Biomedicines . 2025 Jan; 13(1). PMID: 39857734
Chronic venous disease (CVD) comprises a set of vascular disorders that affect the venous system with important local and systemic repercussions. A growing body of evidence displays the relationship between...
3.
Ortega M, Fraile-Martinez O, Garcia-Montero C, Diaz-Pedrero R, Lopez-Gonzalez L, Monserrat J, et al.
Mil Med Res . 2024 Dec; 11(1):80. PMID: 39681901
Mood disorders include a set of psychiatric manifestations of increasing prevalence in our society, being mainly represented by major depressive disorder (MDD) and bipolar disorder (BD). The etiopathogenesis of mood...
4.
De Leon-Oliva D, Boaru D, Minaya-Bravo A, De Castro-Martinez P, Fraile-Martinez O, Garcia-Montero C, et al.
Heliyon . 2024 Nov; 10(21):e39684. PMID: 39553553
In the face of cell damage, cells can initiate a response ranging from survival to death, the balance being crucial for tissue homeostasis and overall health. Cell death, in both...
5.
Boaru D, Fraile-Martinez O, De Leon-Oliva D, Garcia-Montero C, De Castro-Martinez P, Miranda-Gonzalez A, et al.
Int J Biol Sci . 2024 Nov; 20(14):5608-5672. PMID: 39494333
Inflammatory bowel disease (IBD) encompasses a spectrum of chronic inflammatory conditions affecting the gastrointestinal tract, notably ulcerative colitis (UC) and Crohn's disease (CD). Both UC and CD result from the...
6.
Ortega M, Pekarek T, De Leon-Oliva D, Boaru D, Fraile-Martinez O, Garcia-Montero C, et al.
Biomolecules . 2024 Oct; 14(10). PMID: 39456171
Preeclampsia (PE) is a complex multisystem disease characterized by hypertension of sudden onset (>20 weeks' gestation) coupled with the presence of at least one additional complication, such as proteinuria, maternal...
7.
Ortega M, Boaru D, De Leon-Oliva D, Fraile-Martinez O, Garcia-Montero C, Rios L, et al.
J Mol Med (Berl) . 2024 Jun; 102(8):987-1000. PMID: 38935130
The PD-1/PD-L1 axis is a complex signaling pathway that has an important role in the immune system cells. Programmed cell death protein 1 (PD-1) acts as an immune checkpoint on...
8.
Ortega M, De Leon-Oliva D, Boaru D, Fraile-Martinez O, Garcia-Montero C, Casanova C, et al.
Histol Histopathol . 2024 Jun; 40(2):147-156. PMID: 38832442
Bone defects are due to trauma, infections, tumors, or aging, including bone fractures, bone metastases, osteoporosis, or osteoarthritis. The global burden of these demands research into innovative strategies that overcome...
9.
Fraile-Martinez O, Garcia-Montero C, Fraile-Martinez M, Pekarek L, Barrena-Blazquez S, Lopez-Gonzalez L, et al.
Front Psychol . 2024 May; 15:1387162. PMID: 38817830
The connection between physical activity and cognitive function has become a focus of attention in educational research in recent years. Regular exercise has been shown to have significant positive effects...
10.
Ortega M, Garcia-Puente L, Fraile-Martinez O, Pekarek T, Garcia-Montero C, Bujan J, et al.
Antioxidants (Basel) . 2024 May; 13(5). PMID: 38790696
Preeclampsia, a serious and potentially life-threatening medical complication occurring during pregnancy, is characterized by hypertension and often accompanied by proteinuria and multiorgan dysfunction. It is classified into two subtypes based...