Sihem Cheloufi
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Explore the profile of Sihem Cheloufi including associated specialties, affiliations and a list of published articles.
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26
Citations
3447
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Recent Articles
1.
Liu Y, He S, Pyo A, Zheng S, Chen M, Cheloufi S, et al.
bioRxiv
. 2025 Mar;
PMID: 40027791
Ribonuclease (RNase) MRP is a conserved RNA-based enzyme that is essential for maturation of ribosomal RNA (rRNA) in eukaryotes. However, the composition and RNA substrate specificity of this multisubunit ribonucleoprotein...
2.
Do B, Hsu P, Vermeulen S, Wang Z, Hirz T, Abbott K, et al.
Dev Cell
. 2024 Jun;
59(16):2203-2221.e15.
PMID: 38823395
Control of cellular identity requires coordination of developmental programs with environmental factors such as nutrient availability, suggesting that perturbing metabolism can alter cell state. Here, we find that nucleotide depletion...
3.
Shah K, He S, Turner D, Corbo J, Rebbani K, Dominguez D, et al.
Nat Commun
. 2024 Apr;
15(1):3159.
PMID: 38605040
How RNA-binding proteins (RBPs) convey regulatory instructions to the core effectors of RNA processing is unclear. Here, we document the existence and functions of a multivalent RBP-effector interface. We show...
4.
Shah K, He S, Turner D, Corbo J, Rebbani K, Bateman J, et al.
bioRxiv
. 2023 Oct;
PMID: 37790431
RNA-binding proteins (RBPs) are key regulators of gene expression, but how RBPs convey regulatory instructions to the core effectors of RNA processing is unclear. Here we document the existence and...
5.
He S, Valkov E, Cheloufi S, Murn J
Nat Rev Genet
. 2022 Nov;
24(5):276-294.
PMID: 36418462
RNA-binding proteins (RBPs) regulate essentially every event in the lifetime of an RNA molecule, from its production to its destruction. Whereas much has been learned about RNA sequence specificity and...
6.
Franklin R, Guo Y, He S, Chen M, Ji F, Zhou X, et al.
Nat Commun
. 2022 Apr;
13(1):2350.
PMID: 35487911
Cell fate commitment is driven by dynamic changes in chromatin architecture and activity of lineage-specific transcription factors (TFs). The chromatin assembly factor-1 (CAF-1) is a histone chaperone that regulates chromatin...
7.
Blanco M, Sykes D, Gu L, Wu M, Petroni R, Karnik R, et al.
Cell Rep
. 2021 Nov;
37(6):109967.
PMID: 34758323
Stem and progenitor cells have the capacity to balance self-renewal and differentiation. Hematopoietic myeloid progenitors replenish more than 25 billion terminally differentiated neutrophils every day under homeostatic conditions and can...
8.
Franklin R, Murn J, Cheloufi S
Front Cell Dev Biol
. 2021 May;
9:654915.
PMID: 33959610
An expanding repertoire of histone variants and specialized histone chaperone partners showcases the versatility of nucleosome assembly during different cellular processes. Recent research has suggested an integral role of nucleosome...
9.
Shi J, Zhang Y, Tan D, Zhang X, Yan M, Franklin R, et al.
Nat Cell Biol
. 2021 Apr;
23(6):676.
PMID: 33927371
A Correction to this paper has been published: https://doi.org/10.1038/s41556-021-00687-w.
10.
Shi J, Zhang Y, Tan D, Zhang X, Yan M, Franklin R, et al.
Nat Cell Biol
. 2021 Apr;
23(4):424-436.
PMID: 33820973
Although high-throughput RNA sequencing (RNA-seq) has greatly advanced small non-coding RNA (sncRNA) discovery, the currently widely used complementary DNA library construction protocol generates biased sequencing results. This is partially due...