Sierra J McDonald
Overview
Explore the profile of Sierra J McDonald including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
63
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Recent Articles
1.
Bullard B, McDonald S, Cardaci T, VanderVeen B, Mohammed A, Kubinak J, et al.
Am J Physiol Gastrointest Liver Physiol
. 2024 Mar;
326(5):G591-G606.
PMID: 38469632
Ulcerative colitis (UC) is an idiopathic inflammatory disease of the large intestine, which impacts millions worldwide. Current interventions aimed at treating UC symptoms can have off-target effects, invoking the need...
2.
VanderVeen B, Cardaci T, Bullard B, Huss A, McDonald S, Muhammed A, et al.
Am J Physiol Cell Physiol
. 2024 Jan;
326(2):C606-C621.
PMID: 38189130
Immune cell-driven pathways are linked to cancer cachexia. Tumor presence is associated with immune cell infiltration whereas cytotoxic chemotherapies reduce immune cell counts. Despite these paradoxical effects, both cancer and...
3.
Cardaci T, VanderVeen B, Bullard B, McDonald S, Unger C, Enos R, et al.
J Cachexia Sarcopenia Muscle
. 2023 Dec;
15(1):124-137.
PMID: 38062911
Background: More than 650 million people are obese (BMI > 30) worldwide, which increases their risk for several metabolic diseases and cancer. While cachexia and obesity are at opposite ends...
4.
McDonald S, Bullard B, VanderVeen B, Cardaci T, Chatzistamou I, Fan D, et al.
Physiol Rep
. 2023 Oct;
11(19):e15813.
PMID: 37821408
It has been suspected that tumor resection surgery itself may accelerate breast cancer (BC) lung metastasis in some patients. Emodin, a natural anthraquinone found in the roots and rhizomes of...
5.
McDonald S, Bullard B, VanderVeen B, Cardaci T, Huss A, Fan D, et al.
Am J Physiol Gastrointest Liver Physiol
. 2023 Jul;
325(4):G318-G333.
PMID: 37489869
Currently available colorectal cancer (CRC) therapies have limited efficacy and severe adverse effects that may be overcome with the alternative use of natural compounds. We previously reported that panaxynol (PA),...
6.
VanderVeen B, Cardaci T, Cunningham P, McDonald S, Bullard B, Fan D, et al.
Nutrients
. 2023 Jan;
15(1).
PMID: 36615760
A cachexia diagnosis is associated with a doubling in hospital stay and increased healthcare cost for cancer patients and most cachectic patients do not survive treatment. Unfortunately, complexity in treating...
7.
McDonald S, VanderVeen B, Bullard B, Cardaci T, Madero S, Chatzistamou I, et al.
Physiol Rep
. 2022 Nov;
10(21):e15497.
PMID: 36325601
Approximately one-third of all breast cancer mortality results from metastatic recurrence after initial success of surgery and/or therapy. Although primary tumor removal is widely accepted as beneficial, it has long...
8.
Bullard B, VanderVeen B, McDonald S, Cardaci T, Murphy E
Am J Physiol Gastrointest Liver Physiol
. 2022 Oct;
323(6):G554-G561.
PMID: 36283090
Ulcerative colitis (UC) is a chronic disease that is characterized by diffuse inflammation of the colonic and rectal mucosa. The burden of UC is rising globally with significant disparities in...
9.
McDonald S, Cranford T, VanderVeen B, Cardaci T, Velazquez K, Enos R, et al.
Physiol Genomics
. 2022 Sep;
54(11):433-442.
PMID: 36121133
miRNA155 (miR155) has emerged as an important regulator of breast cancer (BrCa) development. Studies have consistently noted an increase in miR155 levels in serum and/or tissues in patients with BrCa....
10.
VanderVeen B, Cardaci T, Madero S, McDonald S, Bullard B, Price R, et al.
J Appl Physiol (1985)
. 2022 Aug;
133(4):834-849.
PMID: 36007896
5-Fluorouracil (5FU) remains a first-line chemotherapeutic for several cancers despite its established adverse side effects. Reduced blood counts with cytotoxic chemotherapies not only expose patients to infection and fatigue, but...