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Siegfried Goerg

Explore the profile of Siegfried Goerg including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 1287
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Recent Articles
1.
Sazonovs A, Stevens C, Venkataraman G, Yuan K, Avila B, Abreu M, et al.
Nat Genet . 2022 Aug; 54(9):1275-1283. PMID: 36038634
Genome-wide association studies (GWASs) have identified hundreds of loci associated with Crohn's disease (CD). However, as with all complex diseases, robust identification of the genes dysregulated by noncoding variants typically...
2.
Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, et al.
Hum Mol Genet . 2022 Jul; 31(23):3945-3966. PMID: 35848942
Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying...
3.
Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, et al.
N Engl J Med . 2020 Jun; 383(16):1522-1534. PMID: 32558485
Background: There is considerable variation in disease behavior among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19). Genomewide association analysis...
4.
Brueggemann A, Noltze A, Lange T, Kaun M, Gliemroth J, Goerg S, et al.
J Surg Res . 2008 Aug; 150(1):125-30. PMID: 18694577
Background: Free tissue transfer (FTT) represents a clinical model to measure ischemia-reperfusion injury (IRI). This study was conducted to detect substances relevant for IRI after FTT. Methods: Eighteen patients underwent...
5.
Ziemann M, Krueger S, Maier A, Unmack A, Goerg S, Hennig H
Transfusion . 2007 Oct; 47(11):1972-83. PMID: 17958525
Background: Human cytomegalovirus (CMV) is considered to latently infect blood cells. Transfusion-transmitted infection (TT-CMV) of immunocompromised patients occurs despite the use of CMV-seronegative or leukoreduced units. Study Design And Methods:...
6.
Finke D, Randers K, Hoerster R, Hennig H, Zawatzky R, Marion T, et al.
Eur J Immunol . 2007 May; 37(6):1702-9. PMID: 17506029
Systemic lupus erythematosus (SLE), an autoimmune disease characterized by chronic nephritis, arthritis and dermatitis, and the presence of antinuclear autoantibodies, is associated with complement factor deficiencies in the classical activation...
7.
Zachrau B, Finke D, Kropf K, Gosink H, Kirchner H, Goerg S
Int Immunol . 2004 Oct; 16(12):1685-90. PMID: 15477230
Defects of early complement components (C1, C4 and C2) are associated with the development of systemic lupus erythematosus (SLE). The availability of complement knockout mice has increased our knowledge on...
8.
Bugert P, Hoffmann M, Winkelmann B, Vosberg M, Jahn J, Entelmann M, et al.
J Mol Med (Berl) . 2003 Jul; 81(8):495-501. PMID: 12879153
Genes involved in inflammatory processes are candidates for predisposition to prothrombotic syndromes. The variable number of tandem repeat (VNTR) polymorphism in the P-selectin glycoprotein ligand (PSGL)-1 gene has been associated...
9.
Hennig H, Puchta I, Luhm J, Schlenke P, Goerg S, Kirchner H
Blood . 2002 Sep; 100(7):2637-41. PMID: 12239179
The objective of this study was to determine the frequency and load of hepatitis B virus (HBV) DNA in anti-HBc-positive first-time blood donors; it was designed to contribute to determining...
10.
Goerg S
Cell Mol Biol (Noisy-le-grand) . 2002 May; 48(3):237-45. PMID: 12030427
Systemic lupus erythematosus (SLE), an autoimmune disease characterized by chronic nephritis, arthritis or dermatitis and the presence of antinuclear autoantibodies is associated with deficiencies of complement factors of the classical...