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Sicong Zeng

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Articles 27
Citations 227
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Recent Articles
1.
Yuan S, Hu L, Zhong J, Hu X, Zhao X, Wan Z, et al.
Haemophilia . 2024 Dec; 31(1):148-155. PMID: 39632590
Background: Haemophilia A (HA) is a rare bleeding disorder caused by variants in F8. Although traditional mutational analyses have identified numerous pathogenic variants, the aetiology of HA in certain patients...
2.
Yang Q, Li J, Zeng S, Li Z, Liu X, Li J, et al.
Stem Cells Dev . 2023 Jul; 32(21-22):681-692. PMID: 37470211
Retinitis pigmentosa (RP) is a prevalent inherited retinal degenerative disease resulting from photoreceptor and pigment epithelial apoptosis. The is the most commonly associated pathogenic gene in RP. However, mutations (c.512C>T...
3.
Hu J, Li J, Dai C, Ren J, Yang W, He C, et al.
Biochem Biophys Res Commun . 2023 Mar; 655:50-58. PMID: 36933307
Serious intestinal side-effects that target the NOTCH-HES1 pathway in human cancer differentiation therapy make it necessary to understand the pathway at the human organ level. Herein, we endogenously introduced HES1-/-...
4.
Wu Y, Zeng S, Miao C, Wu H, Xu X, Chen L, et al.
Gene . 2023 Mar; 866:147350. PMID: 36898512
Cell division cycle associated 8 (CDCA8) is a component of the chromosomal passenger complex and plays an essential role in mitosis, meiosis, cancer growth, and undifferentiated state of embryonic stem...
5.
Zhang X, Zhang C, Zhou D, Zhang T, Chen X, Ren J, et al.
iScience . 2023 Feb; 26(3):106158. PMID: 36843839
Zygotic genome activation (ZGA) is initiated once the genome chromatin state is organized in the newly formed zygote. Telomeres are specialized chromatin structures at the ends of chromosomes and are...
6.
He C, Zhang X, Li J, Dai C, Wang S, Dai C, et al.
Biochem Biophys Res Commun . 2022 Nov; 636(Pt 2):40-47. PMID: 36343489
Telomerase is activated in pluripotent stem cells and the majority of tumors and is postulated to be necessary for the acquisition of self-renewal and long-term proliferation. Placental mesenchymal stem cells...
7.
Liu J, Zeng S, Wang Y, Yu J, Ouyang Q, Hu L, et al.
Stem Cells Int . 2020 Oct; 2020:5823676. PMID: 33029148
Human embryonic stem cells (hESCs) gradually accumulate abnormal karyotypes during long-term suboptimal culture, which hinder their application in regenerative medicine. Previous studies demonstrated that the activation of might be implicated...
8.
Dai C, Cheng D, Li W, Zeng S, Lu G, Zhang Q
Mol Genet Genomic Med . 2020 Jul; 8(9):e1394. PMID: 32643877
Background: Prezygotic de novo mutations may be inherited from parents with germline mosaicism and are often overlooked when the resulting phenotype affects only one child. We aimed to identify paternal...
9.
Dai C, Zeng S, Tan Z, Yang X, Du J, Lu G, et al.
Clin Genet . 2019 Jul; 96(4):380-381. PMID: 31322726
No abstract available.
10.
He C, Jing S, Dai C, Tu C, Tan Z, Du J, et al.
Mol Genet Genomic Med . 2019 May; 7(7):e00709. PMID: 31119896
Background: Dyskeratosis congenita (DC) is a rare heritable bone marrow failure syndrome that is associated with telomere dysfunction, and has high genetic heterogeneity and varied features. Objective: This study aimed...