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Shuyi Chong

Explore the profile of Shuyi Chong including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 164
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Recent Articles
1.
Pan R, Yu Y, Zhu H, Zhang W, Qin Y, Ye L, et al.
iScience . 2022 Oct; 25(10):105184. PMID: 36217544
R-spondin 2 (RSPO2) drives the potentiation of Wnt signaling and is implicated in tumorigenesis in multiple cancers, but its role in ovarian cancer has not been investigated. Here, we reported...
2.
Qin Y, Wu K, Zhang Z, Pan R, Lin Z, Zhang W, et al.
Biochim Biophys Acta Mol Basis Dis . 2022 Aug; 1868(11):166518. PMID: 35963285
Cutaneous wound healing is a complicated process that is characterized by an initial inflammatory phase followed by a proliferative phase. NLRC3 plays important roles in innate immunity, inflammatory regulation and...
3.
Zhang W, Pan R, Lu M, Zhang Q, Lin Z, Qin Y, et al.
Oncogene . 2021 Sep; 40(45):6369-6380. PMID: 34588619
The therapeutic efficacy of 5-fluorouracil (5-FU) is often reduced by the development of drug resistance. We observed significant upregulation of lipocalin 2 (LCN2) expression in a newly established 5-FU-resistant colorectal...
4.
Wang X, Chong S, Lin H, Yan Z, Huang F, Zeng Z, et al.
Bioorg Chem . 2019 Jan; 85:413-419. PMID: 30665035
Retinoid X receptor alpha (RXRα), a central member of the nuclear receptor superfamily and a key regulator of many signal transduction pathways, has been an attractive drug target. We previously...
5.
Yan Z, Chong S, Lin H, Yang Q, Wang X, Zhang W, et al.
Eur J Med Chem . 2019 Jan; 164:562-575. PMID: 30634084
Nuclear receptor RXRα plays an important role in many biological and pathological processes. The nongenomic action of RXRα is implicated in many cancers. K-8008, a non-canonical RXRα ligand derived from...
6.
Hu M, Luo Q, Alitongbieke G, Chong S, Xu C, Xie L, et al.
Mol Cell . 2017 Apr; 66(1):141-153.e6. PMID: 28388439
Mitochondria play an integral role in cell death, autophagy, immunity, and inflammation. We previously showed that Nur77, an orphan nuclear receptor, induces apoptosis by targeting mitochondria. Here, we report that...