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Shuwen Guan

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Articles 36
Citations 257
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Recent Articles
11.
Ke J, Zhang J, Li J, Liu J, Guan S
Int J Mol Sci . 2022 Oct; 23(20). PMID: 36292932
In recent years, cyclic peptides have attracted much attention due to their chemical and enzymatic stability, low toxicity, and easy modification. In general, the self-assembled nanostructures of cyclic peptides tend...
12.
Zhang J, Guan S, Zhang C, Du X, Li T, Xiao S
J Clin Sleep Med . 2022 Oct; 19(2):303-308. PMID: 36263860
Study Objectives: To investigate the feasibility and effectiveness of nasopharyngeal tube (NPT) insertion in alleviating sleep hypoxemia during the first night after velopharyngeal surgery in patients with obstructive sleep apnea...
13.
Guan S, Gao B, Xiao J
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi . 2022 Aug; 39(4):776-783. PMID: 36008342
Primary human hepatocytes (PHH) are the gold standard of human liver model for drug screening. However, a problem of culturing PHH is the rapid decline of cytochrome P450 (CYP450) activity,...
14.
Xiao J, Li X, Zhou Z, Guan S, Zhuo L, Gao B
Biosci Trends . 2022 Aug; 16(4):257-266. PMID: 35965099
The evidence shows that there is an associated relationship between hepatosteatosis and insulin resistance. While some existing genetic induction animal and patient models challenge this relationship, indicating that hepatosteatosis is...
15.
Zhou Z, Xiao J, Guan S, Geng Z, Zhao R, Gao B
Carbohydr Polym . 2022 Mar; 285:119235. PMID: 35287859
Manufacturing facile and low-cost wound dressings that simultaneously meet the needs of the entire repair process remains the major challenge of effective wound healing. Herein, a series of curdlan-tannic acid...
16.
Yu X, Li H, Lin D, Guo W, Xu Z, Wang L, et al.
Int J Mol Sci . 2021 Sep; 22(18). PMID: 34575832
is a valuable traditional Chinese medicine in Northeast China. Ginsenoside, the active component of ginseng, has not been investigated much for its effects on aging and its underlying mechanism(s) of...
17.
Li H, Yu X, Meng F, Zhao Z, Guan S, Wang L
Int J Mol Sci . 2021 Apr; 22(8). PMID: 33924155
Ferulic acid (FA) is a naturally-occurring well-known potent antioxidant and free radical scavenger. FA supplementation is an effective strategy to delay aging, but the underlying mechanism remains unknown. In the...
18.
Li H, Yu X, Li C, Ma L, Zhao Z, Guan S, et al.
Food Funct . 2021 Jan; 12(3):1219-1231. PMID: 33432954
Caffeic acid (CA), a derivative of cinnamic acid, exists in various vegetables and fruits. Natural compounds as beneficial antioxidants play an important role in the research of Alzheimer's disease (AD)....
19.
Huang Z, Guan S, Wang Y, Shi G, Cao L, Gao Y, et al.
J Mater Chem B . 2020 Apr; 1(17):2297-2304. PMID: 32260883
Herein, we report the construction of a novel hydrolase model via self-assembly of a synthetic amphiphilic short peptide (Fmoc-FFH-CONH) into nanotubes. The peptide-based self-assembled nanotubes (PepNTs-His) with imidazolyl groups as...
20.
Han W, Yuan Y, Li H, Fu Z, Wang M, Guan S, et al.
Colloids Surf B Biointerfaces . 2019 Aug; 183:110385. PMID: 31408781
Polypeptide carriers have a good cell compatibility, rich functionality, and facile synthesis and modification, make them promising materials as siRNA vectors. Phenylalanine dipeptide (FF) has been previously assessed as an...