Shunsuke Hazama
Overview
Explore the profile of Shunsuke Hazama including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
190
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Recent Articles
1.
Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons
Koshimizu H, Hazama S, Hara T, Ogura A, Kojima M
Neurosci Lett
. 2010 Mar;
473(3):229-32.
PMID: 20219632
Recent studies have focused on a distinctive contrast between bioactivities of precursor brain-derived neurotrophic factor (proBDNF) and mature BDNF (matBDNF). In this study, using a proteolytic cleavage-resistant proBDNF mutant (CR-proBDNF),...
2.
Koshimizu H, Kiyosue K, Hara T, Hazama S, Suzuki S, Uegaki K, et al.
Mol Brain
. 2009 Aug;
2:27.
PMID: 19674479
Background: Proneurotrophins and mature neurotrophins elicit opposite effects via the p75 neurotrophin receptor (p75(NTR)) and Trk tyrosine kinase receptors, respectively; however the molecular roles of proneurotrophins in the CNS are...
3.
Suzuki S, Kiyosue K, Hazama S, Ogura A, Kashihara M, Hara T, et al.
J Neurosci
. 2007 Jun;
27(24):6417-27.
PMID: 17567802
Brain-derived neurotrophic factor (BDNF) exerts multiple biological functions in the CNS. Although BDNF can control transcription and protein synthesis, it still remains open to question whether BDNF regulates lipid biosynthesis....