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Shubham Choudhury

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Articles 12
Citations 55
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Recent Articles
1.
Rathore A, Kumar N, Choudhury S, Mehta N, Raghava G
Commun Biol . 2025 Feb; 8(1):176. PMID: 39905233
Peptide-based drugs often fail in clinical trials due to their toxicity or hemolytic activity against red blood cells (RBCs). Existing methods predict hemolytic peptides but not the concentration (HC) required...
2.
Gahlot P, Choudhury S, Bajiya N, Kumar N, Raghava G
Proteomics . 2024 Nov; :e202400261. PMID: 39580673
Plant disease resistance (PDR) proteins are critical in identifying plant pathogens. Predicting PDR protein is essential for understanding plant-pathogen interactions and developing strategies for crop protection. This study proposes a...
3.
Kumar N, Choudhury S, Bajiya N, Patiyal S, Raghava G
Proteomics . 2024 Sep; 25(3):e202400157. PMID: 39305039
Prediction of antifreeze proteins (AFPs) holds significant importance due to their diverse applications in healthcare. An inherent limitation of current AFP prediction methods is their reliance on unreviewed proteins for...
4.
Rathore A, Choudhury S, Arora A, Tijare P, Raghava G
Comput Biol Med . 2024 Jul; 179:108926. PMID: 39038391
Toxicity emerges as a prominent challenge in the design of therapeutic peptides, causing the failure of numerous peptides during clinical trials. In 2013, our group developed ToxinPred, a computational method...
5.
Tomer R, Patiyal S, Kaur D, Choudhury S, Raghava G
Adv Protein Chem Struct Biol . 2024 Mar; 139:383-403. PMID: 38448141
An uncommon opportunistic fungal infection known as mucormycosis is caused by a class of molds called mucoromycetes. Currently, antifungal therapy and surgical debridement are the primary treatment options for mucormycosis....
6.
Bajiya N, Choudhury S, Dhall A, Raghava G
Antibiotics (Basel) . 2024 Feb; 13(2). PMID: 38391554
Most of the existing methods developed for predicting antibacterial peptides (ABPs) are mostly designed to target either gram-positive or gram-negative bacteria. In this study, we describe a method that allows...
7.
Choudhury S, Bajiya N, Patiyal S, Raghava G
Front Bioinform . 2024 Feb; 4:1341479. PMID: 38379813
In the past, several methods have been developed for predicting the single-label subcellular localization of messenger RNA (mRNA). However, only limited methods are designed to predict the multi-label subcellular localization...
8.
Dhall A, Patiyal S, Choudhury S, Jain S, Narang K, Raghava G
Comput Biol Med . 2023 May; 160:106929. PMID: 37126926
Tumor Necrosis Factor alpha (TNF-α) is a pleiotropic pro-inflammatory cytokine that is crucial in controlling the signaling pathways within the immune cells. Recent studies reported that higher expression levels of...
9.
Aggarwal S, Dhall A, Patiyal S, Choudhury S, Arora A, Raghava G
Front Microbiol . 2023 Apr; 14:1148579. PMID: 37032893
Phage therapy is a viable alternative to antibiotics for treating microbial infections, particularly managing drug-resistant strains of bacteria. One of the major challenges in designing phage-based therapy is to identify...
10.
Mukhopadhyay A, Choudhury S, Kumar M
Virus Res . 2023 Apr; 330:199110. PMID: 37031921
Virome exploration from the freshwater stream ecosystem is less explored. We deciphered the DNA virome from sediments of the N-Choe stream in Chandigarh, India. This study utilized the long-read nanopore...