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Shubana Kazi

Explore the profile of Shubana Kazi including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 192
Followers 0
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Recent Articles
1.
Ogmundsdottir M, Heublein S, Kazi S, Reynolds B, Visvalingam S, Shaw M, et al.
PLoS One . 2012 May; 7(5):e36616. PMID: 22574197
Mammalian Target of Rapamycin Complex 1 (mTORC1) is activated by growth factor-regulated phosphoinositide 3-kinase (PI3K)/Akt/Rheb signalling and extracellular amino acids (AAs) to promote growth and proliferation. These AAs induce translocation...
2.
Reynolds B, Roversi P, Laynes R, Kazi S, Boyd C, Goberdhan D
Biochem J . 2009 Apr; 420(3):363-72. PMID: 19335336
Mammalian CD98 heterodimeric amino acid transporters consist of a promiscuous single-pass transmembrane glycoprotein, CD98hc (CD98 heavy chain), and one of six multipass transmembrane proteins or 'light chains'. The heterodimeric complexes...
3.
Goberdhan D, Ogmundsdottir M, Kazi S, Reynolds B, Visvalingam S, Wilson C, et al.
Biochem Soc Trans . 2009 Jan; 37(Pt 1):248-52. PMID: 19143641
mTOR (mammalian target of rapamycin) plays a key role in determining how growth factor, nutrient and oxygen levels modulate intracellular events critical for the viability and growth of the cell....
4.
Ginger R, Askew S, Ogborne R, Wilson S, Ferdinando D, Dadd T, et al.
J Biol Chem . 2008 Jan; 283(9):5486-95. PMID: 18166528
A non-synonymous single nucleotide polymorphism in the human SLC24A5 gene is associated with natural human skin color variation. Multiple sequence alignments predict that this gene encodes a member of the...
5.
Gardner R, Kazi S, Ellis E
Toxicol Lett . 2004 Mar; 148(1-2):65-72. PMID: 15019089
Acrolein is a highly reactive hazardous air pollutant of human health concern, particularly as it is a component of cigarette smoke. It can be metabolized by enzymes including the aldo-keto...
6.
Kazi S, Ellis E
Chem Biol Interact . 2002 Jun; 140(2):121-35. PMID: 12076520
The glutathione-S-transferases (GST) are a major contributor to the eukaryotic cell's defences against chemical and oxidative stress. However, the role of individual GST isoenzymes in conferring resistance to xenobiotics has...