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Shu Shu

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Articles 36
Citations 435
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Recent Articles
1.
Tang H, Shu S, Hu S, Chen L
Curr Eye Res . 2024 Jun; 49(10):1042-1053. PMID: 38940233
Purpose: Posterior capsule opacification (PCO) is the major complication of visual impairment after cataract surgery. Circular RNAs (circRNAs) are involved in the development of many diseases. The purpose of this...
2.
Mao R, Hu M, Liu X, Ye L, Xu B, Sun M, et al.
Cell Commun Signal . 2024 Feb; 22(1):147. PMID: 38388921
Background: Patients with Alzheimer's disease (AD) are often co-morbid with unprovoked seizures, making clinical diagnosis and management difficult. Although it has an important role in both AD and epilepsy, abnormal...
3.
Ye L, Hu M, Mao R, Tan Y, Sun M, Jia J, et al.
CNS Neurosci Ther . 2023 Dec; 30(6):e14555. PMID: 38105588
Aims: Synaptic dysfunction is a hallmark pathology of Alzheimer's disease (AD) and is strongly associated with cognitive impairment. Abnormal phagocytosis by the microglia is one of the main causes of...
4.
Xu S, Jia J, Sun M, Bao X, Xia S, Shu S, et al.
iScience . 2023 Jul; 26(7):107268. PMID: 37496671
Ischemic stroke is the second leading cause of death worldwide, and there are limited effective treatment strategies. QHRD106, a polyethyleneglycol (PEG)-modified long-acting tissue kallikrein preparation, has not been reported previously....
5.
Ge J, Xue Z, Shu S, Yu L, Qin R, Tao W, et al.
JCI Insight . 2023 May; 8(12). PMID: 37192007
Synaptic plasticity impairment plays a critical role in the pathogenesis of Alzheimer's disease (AD), and emerging evidence has shown that microRNAs (miRs) are alternative biomarkers and therapeutic targets for synaptic...
6.
Ye L, Shu S, Jia J, Sun M, Xu S, Bao X, et al.
Aging Cell . 2023 May; 22(7):e13860. PMID: 37177836
Pattern separation (PS) dysfunction is a type of cognitive impairment that presents early during the aging process, and this deficit has been attributed to structural and functional alterations in the...
7.
Cao Q, Chen J, Zhang Z, Shu S, Qian Y, Yang L, et al.
J Neuroinflammation . 2023 May; 20(1):105. PMID: 37138312
Background: Chronic cerebral ischemia induces white matter injury (WMI) contributing to cognitive decline. Both astrocytes and microglia play vital roles in the demyelination and remyelination processes, but the underlying mechanism...
8.
Jia J, Zheng L, Ye L, Chen J, Shu S, Xu S, et al.
Cell Death Dis . 2023 Feb; 14(2):156. PMID: 36828819
Ischemic stroke leads to white matter damage and neurological deficits. However, the characteristics of white matter injury and repair after stroke are unclear. Additionally, the precise molecular communications between microglia...
9.
Deng S, Shu S, Zhai L, Xia S, Cao X, Li H, et al.
Adv Sci (Weinh) . 2022 Dec; 10(5):e2202976. PMID: 36529961
White matter injury (WMI), which reflects myelin loss, contributes to cognitive decline or dementia caused by cerebral vascular diseases. However, because pharmacological agents specifically for WMI are lacking, novel therapeutic...
10.
Shu S, Xu S, Ye L, Liu Y, Cao X, Jia J, et al.
Neuropsychopharmacology . 2022 Oct; 48(2):391-401. PMID: 36229597
Alzheimer's disease (AD) is the most common neurodegenerative disease and has an insidious onset. Exploring the characteristics and mechanism of the early symptoms of AD plays a critical role in...