Shruthi Hamsanathan
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Explore the profile of Shruthi Hamsanathan including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
123
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Recent Articles
1.
Hamsanathan S, Anthonymuthu T, Prosser D, Lokshin A, Greenspan S, Resnick N, et al.
Aging Cell
. 2024 Mar;
23(4):e14104.
PMID: 38454639
Unlike chronological age, biological age is a strong indicator of health of an individual. However, the molecular fingerprint associated with biological age is ill-defined. To define a high-resolution signature of...
2.
Hamsanathan S, Gurkar A
Front Physiol
. 2022 Apr;
13:796850.
PMID: 35370799
Lipids are key macromolecules that perform a multitude of biological functions ranging from maintaining structural integrity of membranes, energy storage, to signaling molecules. Unsurprisingly, variations in lipid composition and its...
3.
Hamsanathan S, Anthonymuthu T, Han S, Shinglot H, Siefken E, Sims A, et al.
Sci Adv
. 2022 Feb;
8(7):eabl6083.
PMID: 35171671
Although DNA damage is intricately linked to metabolism, the metabolic alterations that occur in response to DNA damage are not well understood. We use a DNA repair-deficient model of ERCC1-XPF...
4.
Marchal L, Hamsanathan S, Karthikappallil R, Han S, Shinglot H, Gurkar A
Mech Ageing Dev
. 2021 Sep;
200:111573.
PMID: 34562508
Although the link between DNA damage and aging is well accepted, the role of different DNA repair proteins on functional/physiological aging is not well-defined. Here, using Caenorhabditis elegans, we systematically...
5.
Hamsanathan S, Alder J, Sellares J, Rojas M, Gurkar A, Mora A
Am J Respir Cell Mol Biol
. 2019 Apr;
61(1):21-30.
PMID: 30965013
Senescence is a cell fate decision characterized by irreversible arrest of proliferation accompanied by a senescence-associated secretory phenotype. Traditionally, cellular senescence has been recognized as a beneficial physiological mechanism during...
6.
Hamsanathan S, Musser S
FEMS Microbiol Lett
. 2018 Jun;
365(12).
PMID: 29897510
The Tat machinery catalyzes the transport of folded proteins across the cytoplasmic membrane in bacteria and the thylakoid membrane in plants. Transport occurs only in the presence of an electric...
7.
Hamsanathan S, Anthonymuthu T, Bageshwar U, Musser S
Biophys J
. 2017 Dec;
113(12):2650-2668.
PMID: 29262359
The Tat machinery catalyzes the transport of folded proteins across the bacterial cytoplasmic membrane and the thylakoid membrane in plants. Using fluorescence quenching and cross-linking approaches, we demonstrate that the...
8.
Bageshwar U, VerPlank L, Baker D, Dong W, Hamsanathan S, Whitaker N, et al.
PLoS One
. 2016 Feb;
11(2):e0149659.
PMID: 26901445
The twin arginine translocation (Tat) pathway transports fully-folded and assembled proteins in bacteria, archaea and plant thylakoids. The Tat pathway contributes to the virulence of numerous bacterial pathogens that cause...