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Shoya Yamada

Explore the profile of Shoya Yamada including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 122
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Recent Articles
1.
Yamada Y, Niwa T, Ono Y, Yamada S, Niwa K, Yasue M, et al.
J Antimicrob Chemother . 2023 Oct; 78(12):2933-2937. PMID: 37889089
Objectives: Although use of AUC-guided vancomycin dosing was recommended in the revised 2020 consensus guideline, collection of multiple vancomycin serum samples to calculate AUC may cause clinical complications. AUC calculated...
2.
Nishida S, Kato T, Hayashi Y, Yamada S, Fujii H, Yamada M, et al.
J Diabetes Investig . 2023 Jun; 14(10):1202-1208. PMID: 37357565
Aims/introduction: Polypharmacy in diabetes patients is related to worse clinical outcomes. The aim of this study was to evaluate the usefulness of our countermeasure for polypharmacy, which combines a pharmacist...
3.
Kawasaki M, Motoyama T, Yamada S, Watanabe M, Fujihara M, Kambe A, et al.
ACS Med Chem Lett . 2023 Mar; 14(3):291-296. PMID: 36923911
Retinoid X receptor (RXR), a nuclear receptor (NR) that regulates transcription of target genes in a ligand binding-dependent manner, is of interest as a drug target. RXR agonists have been...
4.
Takioku M, Takamura Y, Fujihara M, Watanabe M, Yamada S, Kawasaki M, et al.
ACS Med Chem Lett . 2021 Jun; 12(6):1024-1029. PMID: 34141088
Retinoid X receptor (RXR) ligands often bind in modes in which the carboxy group forms a hydrogen bond inside the ligand-binding pocket (LBP). However, our previously reported RXR antagonist, CBTF-EE...
5.
Yukawa-Takamatsu K, Wang Y, Watanabe M, Takamura Y, Fujihara M, Nakamura-Nakayama M, et al.
J Med Chem . 2020 Dec; 64(1):861-870. PMID: 33378197
Retinoid X receptor (RXR) modulators (rexinoids) are considered to have therapeutic potential for multiple diseases, such as Alzheimer's disease and Parkinson's disease. To overcome various disadvantages of prior screening methods,...
6.
Watanabe M, Fujihara M, Motoyama T, Kawasaki M, Yamada S, Takamura Y, et al.
J Med Chem . 2020 Dec; 64(1):430-439. PMID: 33356247
Retinoid X receptor (RXR) heterodimers such as PPAR/RXR, LXR/RXR, and FXR/RXR can be activated by RXR agonists alone and are therefore designated as permissive. Similarly, existing RXR antagonists show allosteric...
7.
Yamada S, Takamura Y, Fujihara M, Kawasaki M, Ito S, Nakano S, et al.
Bioorg Med Chem Lett . 2020 Nov; 31:127666. PMID: 33152377
Ligands of retinoid X receptors (RXRs) are effective against various diseases, so there is a need for efficient screening methods to discover new ligands. Existing screening methods are complex and...
8.
Yamada S, Ozaki H, Noguchi K
Plant Cell Physiol . 2019 Oct; 61(2):283-295. PMID: 31603217
The plant respiratory chain includes the ATP-coupling cytochrome pathway (CP) and ATP-uncoupling alternative oxidase (AOX). Under high-light (HL) conditions, plants experience photoinhibition, leading to a damaged photosystem II (PSII). The...
9.
Yamada S, Kawasaki M, Fujihara M, Watanabe M, Takamura Y, Takioku M, et al.
J Med Chem . 2019 Sep; 62(19):8809-8818. PMID: 31483660
Ligands for retinoid X receptors (RXRs), "rexinoids", are attracting interest as candidates for therapy of type 2 diabetes and Alzheimer's and Parkinson's diseases. However, current screening methods for rexinoids are...
10.
Takamura Y, Shibahara O, Watanabe M, Fujihara M, Yamada S, Akehi M, et al.
Bioorg Med Chem . 2019 Jun; 27(14):3128-3134. PMID: 31176570
Bexarotene (1), a retinoid X receptor (RXR) agonist approved for the treatment of cutaneous T cell lymphoma (CTCL), was reported to migrate into baboon brain based on findings obtained by...