Shiyin Ooi
Overview
Explore the profile of Shiyin Ooi including associated specialties, affiliations and a list of published articles.
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12
Citations
166
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0
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Recent Articles
1.
Chai A, Tan Y, Ooi S, Yee P, Yee S, Cheong S
Heliyon
. 2024 Nov;
10(21):e39677.
PMID: 39524880
Oral squamous cell carcinoma (OSCC) is known to be driven by multiple intricated receptor tyrosine kinases (RTKs) including EGFR, PI3K/AKT and MAPK signaling pathways. However, whilst targeting EGFR with cetuximab...
2.
Chai A, Tan Y, Ooi S, Yee P, Yee S, Lightfoot H, et al.
Cancer Res Commun
. 2024 Oct;
4(11):2919-2932.
PMID: 39360810
Mechanistically guided drug repurposing has been made possible by systematically integrating pharmacologic and CRISPR-Cas9 screen data. Our study discovers the biomarker and cell death mechanisms underpinning sensitivity toward AZD5582, an...
3.
Liao Y, Huang J, Liu P, Zhang C, Liu J, Xia M, et al.
Oncogene
. 2022 Feb;
41(13):1931-1943.
PMID: 35152264
Epithelial-mesenchymal transition (EMT) is an essential step to drive the metastatic cascade to lymph nodes (LNs) in cervical cancer cells. However, few of them metastasize successfully partially due to increased...
4.
Zhang C, Liu P, Huang J, Liao Y, Pan C, Liu J, et al.
Cell Death Dis
. 2021 Sep;
12(10):888.
PMID: 34588429
Circular RNAs (circRNAs) are known to act as key regulators in a variety of malignancies. However, the role of circRNAs in cervical cancer (CCa) remains largely unknown. Herein, we demonstrated...
5.
Zhou Y, Liao Y, Zhang C, Liu J, Wang W, Huang J, et al.
Stem Cells Int
. 2021 Jul;
2021:6550388.
PMID: 34306095
Cancer stem cells are a key population participating in the promotion of the cervical cancer progression through interacting with cancer cells. Existing studies have preliminary revealed that cervical cancer stem...
6.
Chen J, Xia Y, Liu T, Lai Y, Yu J, Zhang T, et al.
BMC Cancer
. 2021 May;
21(1):532.
PMID: 33971833
Background: The clinical staging systems for adenocarcinoma of the esophagogastric junction (AEG) are controversial. We aimed to propose a prognostic nomogram based on real-world data for predicting survival of Siewert...
7.
Liu T, Chen J, Du Q, Liu J, Chen M, Ooi S, et al.
Pathol Res Pract
. 2021 May;
222:153450.
PMID: 33962175
Family with sequence similarity 83 member A (FAM83A) is a member of the FAM83 family and is proven to have oncogenic properties in several cancers. However, the mechanisms of FAM83A...
8.
Ooi S, Liao Y, Liu P, Xu G, Liu T, Yao S
Gynecol Obstet Invest
. 2020 Oct;
85(5):377-387.
PMID: 33053555
Aim: HPV-negative cervical cancer (CC) usually appears more aggressive and causes poorer survival outcomes compared to HPV-positive cases. However, the research in regard to HPV-negative CC is rare, and the...
9.
Liu P, Zhang C, Liao Y, Liu J, Huang J, Xia M, et al.
Cell Death Dis
. 2020 Aug;
11(8):687.
PMID: 32826853
The prognosis for cervical cancer (CCa) patients with lymph node metastasis (LNM) is dismal. Elucidation of the molecular mechanisms underlying LNM may provide clinical therapeutic strategies for CCa patients with...
10.
Chen J, Lai Y, Ooi S, Song Y, Li L, Liu T
Breast Cancer Res Treat
. 2020 Aug;
184(2):287-300.
PMID: 32772271
Purpose: BTB domain-containing 7 (BTBD7) has been found to regulate epithelial tissue remodeling and branched organ formation and has been reported to modulate the biological behavior of several cancers. However,...