Shirley L MacDonald
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Explore the profile of Shirley L MacDonald including associated specialties, affiliations and a list of published articles.
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6
Citations
77
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Recent Articles
1.
MacDonald S, Downing I, Atkinson A, Gallagher R, Turner M, Kilpatrick D
Hum Immunol
. 2010 Aug;
71(11):1077-83.
PMID: 20705112
Mannan (or mannose)-binding lectin (MBL) can bind to monocytes and dendritic cells, but the significance of such interactions is unknown. We hypothesized that the presence of MBL might prevent the...
2.
Cedzynski M, Atkinson A, Swierzko A, MacDonald S, Szala A, Zeman K, et al.
Mol Immunol
. 2009 Sep;
47(2-3):415-9.
PMID: 19767106
We previously reported an association between relative L-ficolin deficiency and recurrent respiratory infections co-existing with allergic disorders in children. To confirm and extend this preliminary finding, we performed a prospective...
3.
Swierzko A, Cedzynski M, Domzalska-Popadiuk I, MacDonald S, Borkowska-Klos M, Atkinson A, et al.
Mol Immunol
. 2009 Mar;
46(8-9):1696-701.
PMID: 19307021
One collectin (mannan-binding lectin, MBL) and three ficolins (M-ficolin/ficolin-1, L-ficolin/ficolin-2 and H-ficolin/ficolin-3) share the capability to activate complement via the lectin pathway. This property depends on the ability of these...
4.
MacDonald S, Downing I, Turner M, Kilpatrick D
Biochem Soc Trans
. 2008 Nov;
36(Pt 6):1497-500.
PMID: 19021583
MBL (mannan-binding lectin; also called mannose-binding lectin) is a circulating C-type lectin with a collagen-like region synthesized mainly by the liver. MBL may influence susceptibility to infection in recipients of...
5.
Swierzko A, Szala A, Cedzynski M, Domzalska-Popadiuk I, Borkowska-Klos M, Jopek A, et al.
Hum Immunol
. 2008 Oct;
70(1):68-72.
PMID: 18957309
Circulating mannan (or mannose)-binding lectin (MBL) is genetically determined. Low MBL concentrations are associated with certain point mutations in the human MBL2 gene. Here we report the full MBL2 genotypes...
6.
Swierzko A, Atkinson A, Cedzynski M, MacDonald S, Szala A, Domzalska-Popadiuk I, et al.
Mol Immunol
. 2008 Oct;
46(4):551-8.
PMID: 18950864
Ficolins and one collectin, mannan-binding lectin (MBL), are the only factors known to activate the lectin pathway (LP) of complement. There is considerable circumstantial evidence that MBL insufficiency can increase...