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Shinya Takazaki

Explore the profile of Shinya Takazaki including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 244
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Recent Articles
1.
Kuma H, Matsuda R, Nakashima A, Motoyama K, Takazaki S, Hatae H, et al.
Thromb Res . 2018 Jun; 168:60-62. PMID: 29908390
No abstract available.
2.
Abe Y, Kubota M, Takazaki S, Ito Y, Yamamoto H, Kang D, et al.
Protein Sci . 2016 Jun; 25(9):1637-47. PMID: 27291073
Asn46Asp/Asp52Ser or Asn46Glu/Asp52Ser hen egg white lysozyme (HEL) mutant was designed by introducing the substituted catalytic residue Asp46 or Glu46, respectively, based on Venerupis philippinarum (Vp) lysozyme structure as a...
3.
Fang J, Uchiumi T, Yagi M, Matsumoto S, Amamoto R, Takazaki S, et al.
Biosci Rep . 2012 Dec; 33(2):e00021. PMID: 23216091
Some mutations of the DHODH (dihydro-orotate dehydrogenase) gene lead to postaxial acrofacial dysostosis or Miller syndrome. Only DHODH is localized at mitochondria among enzymes of the de novo pyrimidine biosynthesis...
4.
Fang J, Uchiumi T, Yagi M, Matsumoto S, Amamoto R, Saito T, et al.
Biosci Rep . 2012 Sep; 32(6):631-9. PMID: 22967083
Miller syndrome is a recessive inherited disorder characterized by postaxial acrofacial dysostosis. It is caused by dysfunction of the DHODH (dihydroorotate dehydrogenase) gene, which encodes a key enzyme in the...
5.
Yagi M, Uchiumi T, Takazaki S, Okuno B, Nomura M, Yoshida S, et al.
Nucleic Acids Res . 2012 Aug; 40(19):9717-37. PMID: 22904065
p32 is an evolutionarily conserved and ubiquitously expressed multifunctional protein. Although p32 exists at diverse intra and extracellular sites, it is predominantly localized to the mitochondrial matrix near the nucleoid...
6.
Fujino T, Ide T, Yoshida M, Onitsuka K, Tanaka A, Hata Y, et al.
Mitochondrion . 2012 Jun; 12(4):449-58. PMID: 22709542
The overexpression of mitochondrial transcription factor A (TFAM) attenuates the decrease in mtDNA copy number after myocardial infarction, ameliorates pathological hypertrophy, and markedly improves survival. However, non-transgenic strategy to increase...
7.
Nakata Y, Taniguchi G, Takazaki S, Oda-Ueda N, Miyahara K, Ohshima Y
J Biosci Bioeng . 2012 Jun; 114(3):334-41. PMID: 22677066
Common pumpkin plants (Cucurbita maxima) produce fruits of 1-2 kg size on the average, while special varieties of the same species called Atlantic Giant are known to produce a huge...
8.
Matsumoto S, Uchiumi T, Saito T, Yagi M, Takazaki S, Kanki T, et al.
Mitochondrion . 2012 Mar; 12(3):391-8. PMID: 22406259
The mitochondrial oxidative phosphorylation (OXPHOS) proteins are encoded by both nuclear and mitochondrial DNA. The nuclear-encoded OXPHOS mRNAs have specific subcellular localizations, but little is known about which localize near...
9.
Matsumoto S, Uchiumi T, Tanamachi H, Saito T, Yagi M, Takazaki S, et al.
Biochem J . 2012 Jan; 443(2):573-84. PMID: 22280412
Mitochondria play key roles in essential cellular functions, such as energy production, metabolic pathways and aging. Growth factor-mediated expression of the mitochondrial OXPHOS (oxidative phosphorylation) complex proteins has been proposed...
10.
Takazaki S, Abe Y, Yamaguchi T, Yagi M, Ueda T, Kang D, et al.
Biochim Biophys Acta . 2011 Dec; 1818(3):658-65. PMID: 22155194
In our previous paper, we demonstrated that Arg 901 in the C-terminal tail of human AE1 (band 3, anion exchanger 1) had a functional role in conformational change during anion...