Shinya Nagaoka
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Explore the profile of Shinya Nagaoka including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
759
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Recent Articles
1.
Hitomi Y, Ueno K, Aiba Y, Nishida N, Kono M, Sugihara M, et al.
Hepatology
. 2024 Apr;
80(4):776-790.
PMID: 38652555
Background And Aims: Previous genome-wide association studies (GWAS) have indicated the involvement of shared (population-nonspecific) and nonshared (population-specific) susceptibility genes in the pathogenesis of primary biliary cholangitis (PBC) among European...
2.
Abiru S, Kugiyama Y, Suehiro T, Motoyoshi Y, Saeki A, Nagaoka S, et al.
J Clin Biochem Nutr
. 2024 Mar;
74(2):162-168.
PMID: 38510683
Zinc deficiency occurs in a variety of diseases, including chronic liver disease (CLD). We investigated the correlation between zinc levels and biochemical and hematological tests in CLD and the effect...
3.
Bekki S, Hashimoto S, Yamasaki K, Komori A, Abiru S, Nagaoka S, et al.
PLoS One
. 2020 Oct;
15(10):e0241002.
PMID: 33085694
Background: We examined serum kynurenine levels in patients with chronic hepatitis C virus infection, and the relationship between serum kynurenine and prognosis in patients with hepatocellular carcinoma (HCC) and chronic...
4.
Matsumoto A, Nishiguchi S, Enomoto H, Tanaka Y, Shinkai N, Okuse C, et al.
J Gastroenterol
. 2020 Jul;
55(10):977-989.
PMID: 32666202
Background: A prospective pilot study of tenofovir disoproxil fumarate (TDF) and pegylated interferon alpha 2a (P-IFN) add-on therapy was conducted to evaluate its efficacy in reducing viral antigen levels in...
5.
Ueno K, Aiba Y, Hitomi Y, Shimoda S, Nakamura H, Gervais O, et al.
Hepatol Commun
. 2020 May;
4(5):724-738.
PMID: 32363322
Genome-wide association studies (GWASs) in European and East Asian populations have identified more than 40 disease-susceptibility genes in primary biliary cholangitis (PBC). The aim of this study is to computationally...
6.
Hitomi Y, Ueno K, Kawai Y, Nishida N, Kojima K, Kawashima M, et al.
Sci Rep
. 2019 Jan;
9(1):102.
PMID: 30643196
Primary biliary cholangitis (PBC) is a chronic and cholestatic autoimmune liver disease caused by the destruction of intrahepatic small bile ducts. Our previous genome-wide association study (GWAS) identified six susceptibility...
7.
Okamoto S, Yamasaki K, Komori A, Abiru S, Nagaoka S, Saeki A, et al.
Clin J Gastroenterol
. 2018 Nov;
12(3):218-222.
PMID: 30465320
Patients with acute hepatitis B (AHB) usually present after developing symptoms; therefore, the temporal kinetics of viral markers during the incubation period have not been documented clearly. We describe an...
8.
Aiba Y, Harada K, Ito M, Suematsu T, Aishima S, Hitomi Y, et al.
Sci Rep
. 2018 Aug;
8(1):11808.
PMID: 30087368
Our recent genome-wide association study found that the NELFCD/CTSZ locus was significantly associated with progression of primary biliary cholangitis (PBC) to jaundice stage in the Japanese population. In this study,...
9.
Sawai H, Nishida N, Khor S, Honda M, Sugiyama M, Baba N, et al.
Sci Rep
. 2018 May;
8(1):7958.
PMID: 29784950
We have performed a genome-wide association study (GWAS) including 473 Japanese HBV (hepatitis B virus)-positive HCC (hepatocellular carcinoma) patients and 516 HBV carriers including chronic hepatitis and asymptomatic carrier individuals...
10.
Oka S, Higuchi T, Furukawa H, Nakamura M, Komori A, Abiru S, et al.
J Hum Genet
. 2018 Mar;
63(6):739-744.
PMID: 29559739
Several studies reported that autoimmune diseases share a number of susceptibility genes. Of these genes, a SNP rs7708392 in TNIP1 was reported to be associated with systemic lupus erythematosus (SLE)....