Shinichi Ota
Overview
Explore the profile of Shinichi Ota including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
577
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Recent Articles
21.
Buijs M, Wijlemans J, Kwak B, Ota S, Geschwind J
J Vasc Interv Radiol
. 2013 Mar;
24(5):737-43.
PMID: 23489770
Purpose: The antiglycolytic agent 3-bromopyruvate (3-BrPA) promotes anticancer effects in multiple tumor models. This study evaluated the therapeutic efficacy of ultrasound (US)-guided intratumoral delivery of 3-BrPA in an orthotopic tumor...
22.
Buijs M, Geschwind J, Syed L, Ganapathy-Kanniappan S, Kunjithapatham R, Wijlemans J, et al.
J Vasc Interv Radiol
. 2012 Nov;
23(12):1685-91.
PMID: 23177115
Purpose: To characterize tumor growth of N1S1 cells implanted into the liver of Sprague-Dawley rats to determine if this model could be used for survival studies. These results were compared...
23.
Nitta N, Tsuchiya K, Sonoda A, Ota S, Ushio N, Takahashi M, et al.
Jpn J Radiol
. 2012 Sep;
30(10):832-9.
PMID: 23001374
Purpose: Our purpose was to investigate the utility of superparamagnetic iron-oxide nanoparticles (SPIO) as a blood-pooling contrast agent at magnetic resonance imaging (MRI). Materials And Methods: We studied four contrast...
24.
Nitta-Seko A, Nitta N, Shiomi M, Sonoda A, Ota S, Tsuchiya K, et al.
Jpn J Radiol
. 2010 Nov;
28(9):656-62.
PMID: 21113749
Purpose: Using Watanabe heritable hyperlipidemic (WHHL) rabbits, we investigated the ability of ultrasonography (US) to detect contrast enhancement of atherosclerotic lesions after intravenous injection of a microbubble contrast agent (MB)...
25.
Loffroy R, Rao P, Kwak B, Ota S, De Lin M, Liapi E, et al.
Korean J Radiol
. 2010 May;
11(3):257-68.
PMID: 20461179
Therapeutic embolization is defined as the voluntary occlusion of one or several vessels, and this is achieved by inserting material into the lumen to obtain transient or permanent thrombosis in...
26.
Ganapathy-Kanniappan S, Geschwind J, Kunjithapatham R, Buijs M, Syed L, Rao P, et al.
Anticancer Res
. 2010 Apr;
30(3):923-35.
PMID: 20393016
Background: Autophagy, a cellular response to stress, plays a role in resistance to chemotherapy in cancer cells. Resistance renders systemic chemotherapy generally ineffective against human hepatocellular carcinoma (HCC). Recently, we...
27.
Loffroy R, Rao P, Ota S, De Lin M, Kwak B, Geschwind J
Cardiovasc Intervent Radiol
. 2010 Mar;
33(6):1088-100.
PMID: 20232200
Acute nonvariceal upper gastrointestinal (UGI) hemorrhage is a frequent complication associated with significant morbidity and mortality. The most common cause of UGI bleeding is peptic ulcer disease, but the differential...
28.
Ganapathy-Kanniappan S, Geschwind J, Kunjithapatham R, Buijs M, Syed L, Rao P, et al.
Assay Drug Dev Technol
. 2010 Jan;
8(2):258-62.
PMID: 20085459
3-Bromopyruvate (3BrPA) is a pyruvate analog known for its alkylating property. Recently, several reports have documented the antiglycolytic and anticancer effects of 3BrPA and its potential for therapeutic applications. 3BrPA-mediated...
29.
Ganapathy-Kanniappan S, Geschwind J, Kunjithapatham R, Buijs M, Vossen J, Tchernyshyov I, et al.
Anticancer Res
. 2010 Jan;
29(12):4909-18.
PMID: 20044597
Background: The pyruvic acid analog 3-bromopyruvate (3BrPA) is an alkylating agent known to induce cancer cell death by blocking glycolysis. The anti-glycolytic effect of 3BrPA is considered to be the...
30.
Ota S, Horigome K, Ishii T, Nakai M, Hayashi K, Kawamura T, et al.
Biochem Biophys Res Commun
. 2009 Aug;
388(2):311-6.
PMID: 19664596
Metformin is widely used as a hypoglycemic agent for the treatment of type 2 diabetes. Both metformin and rotenone, an inhibitor of respiratory chain complex I, suppressed glucose-6-phosphatase (G6pc), a...