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Shinichi Machida

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Articles 56
Citations 731
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Recent Articles
1.
Jahan C, Bonnet-Madin L, Machida S, Sobhian B, Thenin-Houssier S, Benkirane M
Proc Natl Acad Sci U S A . 2025 Mar; 122(11):e2424465122. PMID: 40067888
To ensure optimal replication and spread, viruses have evolved countermeasures to evade type 1 IFN-mediated antiviral activity. During the early viral replication cycle steps until uncoating, the HIV-1 core protects...
2.
Takada S, Gallo S, Silva S, Tanaka H, Pincheira O, Zuniga J, et al.
J Clin Immunol . 2024 Dec; 45(1):55. PMID: 39673647
Anterior gradient 2 (AGR2) is a protein disulfide isomerase that is important for protein processing in the endoplasmic reticulum and is essential for mucin production in the digestive and respiratory...
3.
Yamashita K, Komatsu K, Hattori T, Machida S, Kagi H
The odd hydration number has so far been missing in the water-rich magnesium chloride hydrate series (MgCl·nHO). In this study, magnesium chloride heptahydrate, MgCl·7HO (or MgCl·7DO), which forms at high...
4.
Komatsu K, Hattori T, Klotz S, Machida S, Yamashita K, Ito H, et al.
Nat Commun . 2024 Jun; 15(1):5100. PMID: 38937434
Hydrogen bond symmetrisation is the phenomenon where a hydrogen atom is located at the centre of a hydrogen bond. Theoretical studies predict that hydrogen bonds in ice VII eventually undergo...
5.
Kobayashi H, Komatsu K, Ito H, Machida S, Hattori T, Kagi H
J Phys Chem Lett . 2023 Nov; 14(47):10664-10669. PMID: 37988084
Ice IV is a metastable high-pressure phase of ice in which the water molecules exhibit orientational disorder. Although orientational ordering is commonly observed for other ice phases, it has not...
6.
Thenin-Houssier S, Machida S, Jahan C, Bonnet-Madin L, Abbou S, Chen H, et al.
Sci Adv . 2023 Nov; 9(44):eadh3642. PMID: 37922361
Unintegrated retroviral DNA is transcriptionally silenced by host chromatin silencing factors. Here, we used the proteomics of isolated chromatin segments method to reveal viral and host factors associated with unintegrated...
7.
Aoki M, Aoki-Ogata H, Bulut H, Hayashi H, Takamune N, Kishimoto N, et al.
Sci Adv . 2023 Jul; 9(28):eadg2955. PMID: 37436982
Nuclear localization signal (NLS) of HIV-1 integrase (IN) is implicated in nuclear import of HIV-1 preintegration complex (PIC). Here, we established a multiclass drug-resistant HIV-1 variant (HIV) by consecutively exposing...
8.
Wang W, Artiles K, Machida S, Benkirane M, Jain N, Fire A
bioRxiv . 2023 Jul; PMID: 37398293
Replication of genetic material involves the creation of characteristic termini. Determining these termini is important to refine our understanding of the mechanisms involved in maintaining the genomes of cellular organisms...
9.
Machida S, Diogo Dias J, Benkirane M
Mol Cell . 2022 Dec; 82(23):4401-4402. PMID: 36459981
Not only does Marseillevirus bear the name of the city where it was identified, it also encompasses its values and what makes Marseille a wonderful city. Marseillevirus is unique and...
10.
Yamashita K, Komatsu K, Klotz S, Fabelo O, Fernandez-Diaz M, Abe J, et al.
Proc Natl Acad Sci U S A . 2022 Sep; 119(40):e2208717119. PMID: 36161890
Ice polymorphs show extraordinary structural diversity depending on pressure and temperature. The behavior of hydrogen-bond disorder not only is a key ingredient for their structural diversity but also controls their...