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Shingo Hirashima

Explore the profile of Shingo Hirashima including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 197
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Recent Articles
1.
Uemura K, Togo A, Hiroshige T, Ohta K, Ueda K, Nishihara K, et al.
Prostate . 2024 Apr; 84(9):866-876. PMID: 38590054
Background: A few studies have examined the ultrastructure of prostatic neuroendocrine cells (NECs), and no study has focused on their ultrastructure in three dimensions. In this study, three-dimensional ultrastructural analysis...
2.
Uemura K, Miyazono Y, Hiroshige T, Ohta K, Ueda K, Nishihara K, et al.
Microsc Microanal . 2023 Sep; 29(2):832-840. PMID: 37749734
The ultrastructure of the nuclear envelope (NE) and redundant NE (RNE) of the spermatozoon cannot be observed in detail using conventional electron microscopy. Thus, this study aimed to employ transmission...
3.
Uemura K, Miyazono Y, Hiroshige T, Ohta K, Ueda K, Nishihara K, et al.
Microsc Microanal . 2023 Jul; 29(4):1460-1466. PMID: 37488820
This study aimed to clarify the three-dimensional ultrastructure of head-side mice spermatozoa mitochondria. Six 13-week-old male C57BL/6 mice were deeply anesthetized, perfused with 2% paraformaldehyde, and placed in 2.5% glutaraldehyde...
4.
Kumagai T, Kinoshita B, Hirashima S, Sugiyama H, Park S
ACS Sens . 2023 Feb; 8(2):923-932. PMID: 36740828
Fluorescent molecular rotors are versatile tools for the investigation of biomolecular interactions and the monitoring of microenvironmental changes in biological systems. They can transform invisible information into a fluorescence signal...
5.
Hirashima S, Park S, Sugiyama H
Chemistry . 2023 Jan; 29(24):e202203961. PMID: 36700521
Förster resonance energy transfer (FRET) is an attractive tool for understanding biomolecular dynamics. FRET-based analysis of nucleosomes has the potential to fill the knowledge gaps between static structures and dynamic...
6.
Hirashima S, Ohta K, Togo A, Tsuneyoshi R, Kusukawa J, Nakamura K
Microscopy (Oxf) . 2022 Sep; 72(1):18-26. PMID: 36087097
Dense connective tissue, including the ligament, tendon, fascia and cornea, is formed by regularly arranged collagen fibres synthesized by fibroblasts (Fbs). The mechanism by which fibre orientation is determined remains...
7.
Hiroshige T, Uemura K, Hirashima S, Togo A, Ohta K, Nakamura K, et al.
Sci Rep . 2022 Jun; 12(1):9484. PMID: 35676513
The present study aimed to explore the three-dimensional (3D) ultrastructure of interstitial cells (ICs) within the lamina propria of the murine vas deferens and the spatial relationships between epithelial cells...
8.
Hirashima S, Sugiyama H, Park S
Chembiochem . 2022 Apr; 23(12):e202200222. PMID: 35438834
Among various kinds of fluorine-substituted biomolecules, 2-fluoroadenine (2FA) and its derivatives have been actively investigated as therapeutic reagents, radio-sensitizers, and F NMR probes. In spite of their excellent properties, DNA...
9.
Hirashima S, Ohta K, Rikimaru-Nishi Y, Togo A, Funatsu T, Tsuneyoshi R, et al.
Microscopy (Oxf) . 2022 Mar; 71(3):187-192. PMID: 35325180
Focused ion beamed (FIB) SEM has a higher spatial resolution than other volume-imaging methods owing to the use of ion beams. However, in this method, it is challenging to analyse...
10.
Hino K, Hirashima S, Tsuneyoshi R, Togo A, Hiroshige T, Kusukawa J, et al.
Tissue Cell . 2022 Feb; 75:101714. PMID: 35124366
Early taste buds are formed from placode cells. Placode cells differentiate into Type I-Ⅲ cells at birth; however, the ultrastructure of these first taste cells remain elusive. Here, we used...