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Shin-Ichi Ueno

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Articles 24
Citations 317
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Recent Articles
1.
Furusawa-Nishii E, Solongo B, Rai K, Yoshikawa S, Chiba A, Okuzumi A, et al.
J Neuroinflammation . 2025 Feb; 22(1):38. PMID: 39934862
Recently, the role of T cells in the pathology of α-synuclein (αS)-mediated neurodegenerative disorders called synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy, has...
2.
Okuzumi A, Hatano T, Matsumoto G, Nojiri S, Ueno S, Imamichi-Tatano Y, et al.
Nat Med . 2025 Jan; 31(2):698. PMID: 39856337
No abstract available.
3.
Suzuki S, Akahane T, Tanimoto A, Higashi M, Kitazono I, Kirishima M, et al.
PLoS One . 2025 Jan; 20(1):e0305025. PMID: 39847581
Kinase-related gene fusion and point mutations play pivotal roles as drivers in cancer, necessitating optimized, targeted therapy against these alterations. The efficacy of molecularly targeted therapeutics varies depending on the...
4.
Takeshige-Amano H, Oyama G, Ogawa M, Fusegi K, Kambe T, Shiina K, et al.
Sci Rep . 2024 Nov; 14(1):26309. PMID: 39487204
In super-aged societies, dementia has become a critical issue, underscoring the urgent need for tools to assess cognitive status effectively in various sectors, including financial and business settings. Facial and...
5.
Nishikawa N, Hatano T, Nishioka K, Ueno S, Saiki S, Nakamura R, et al.
J Neurol Sci . 2024 May; 461:123051. PMID: 38788287
Background: Safinamide is an effective adjunctive therapy for wearing-off in Parkinson's disease (PD); however, evidence is lacking in older patients and those in the early stages of wearing-off. This study...
6.
Ishiguro Y, Tsunemi T, Shimada T, Yoroisaka A, Ueno S, Takeshige-Amano H, et al.
Biochem Biophys Res Commun . 2024 Feb; 703:149620. PMID: 38359614
Parkinson's disease (PD) is characterized by the pathological deposition of a-synuclein (a-syn) inclusions, known as Lewy bodies/neurites. Emerging evidence suggests that extracellular vesicles (EVs) play a role in facilitating the...
7.
Hatano T, Oyama G, Shimo Y, Ogaki K, Nishikawa N, Nakamura R, et al.
Mov Disord Clin Pract . 2024 Jan; 11(4):352-362. PMID: 38264844
Background: Chronic constipation is a common digestive complication of Parkinson's disease (PD). Objectives: To verify the usefulness of elobixibat, an ileal bile acid transporter inhibitor, for chronic constipation in PD....
8.
Okuzumi A, Hatano T, Matsumoto G, Nojiri S, Ueno S, Imamichi-Tatano Y, et al.
Nat Med . 2023 May; 29(6):1448-1455. PMID: 37248302
Abnormal α-synuclein aggregation is a key pathological feature of a group of neurodegenerative diseases known as synucleinopathies, which include Parkinson's disease (PD), dementia with Lewy bodies and multiple system atrophy...
9.
Akanuma H, Ueno S, Tanaka S, Matsuda N, Kanai K
Cureus . 2022 Dec; 14(11):e31834. PMID: 36579293
Mollaret meningitis is a recurrent aseptic meningitis mostly caused by herpes simplex virus type 2. Other causes of the disease rarely exist, and its pathology is not well understood. Herein,...
10.
Suzuki S, Hourai S, Uozumi K, Uchida Y, Yoshimitsu M, Miho H, et al.
BMC Cancer . 2022 Oct; 22(1):1065. PMID: 36243685
Background: Activated mutations in NOTCH1 are drivers of T-cell type acute lymphoblastic leukemia/lymphoma. The γ-secretase inhibitor (GSI), which suppresses the function of NOTCH1, is expected to be a molecular-targeted agent....