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Shih-Yi Lee

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Articles 57
Citations 308
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Recent Articles
1.
Lee S, Wu S, Du C, Ku H
Cardiovasc Toxicol . 2024 Jul; 24(10):1090-1104. PMID: 38955919
Oxidative stress causes mitochondrial damage and bioenergetic dysfunction and inhibits adenosine triphosphate production, contributing to the pathogenesis of cardiac diseases. Dipeptidyl peptidase 4 (DPP4) is primarily a membrane-bound extracellular peptidase...
2.
Huang C, Lee S, Du C, Wu S, Kuo Y, Ku H
Biomed Pharmacother . 2024 Feb; 173:116298. PMID: 38394850
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease; its cause is unknown, and it leads to notable health problems. Currently, only two drugs are recommended for...
3.
Huang C, Lee S, Du C, Ku H
Pharmacol Rep . 2023 May; 75(4):1005-1016. PMID: 37233949
Background: Kidney fibrosis is the final manifestation of chronic kidney disease, a condition mainly caused by diabetic nephropathy. Persistent tissue damage leads to chronic inflammation and excessive deposition of extracellular...
4.
Liao W, Lee S, Liao E, Chang W, Chen T, Huang M, et al.
Sci Rep . 2023 Apr; 13(1):6965. PMID: 37117245
The emergency room (ER) digital bedside card is a simple and important invention. It can be directly connected to the hospital information system to display important patient information in real...
5.
Lee S, Kuo Y, Du C, Huang C, Ku H
Biomed Pharmacother . 2023 Apr; 162:114709. PMID: 37084559
Differentiation of cardiac fibroblasts into myofibroblasts is a critical event in the progression of cardiac fibrosis that causes pathological cardiac remodeling. Cardiac fibrosis is a hallmark of heart disease and...
6.
Ku H, Chien D, Chao C, Lee S
J Vis Exp . 2023 Jan; (190). PMID: 36591988
Coronary heart disease is the leading cause of death globally. Complete cessation of blood flow in coronary arteries causes ST-segment elevation myocardial infarction (STEMI), resulting in cardiogenic shock and fatal...
7.
Huang L, Chen S, Hu Y, Liu C, Wu P, Sun S, et al.
Sci Rep . 2022 Jan; 12(1):913. PMID: 35042878
Reassessing the continuing need for and choice of antibiotics by using an antibiotic "time out'' program may reduce unnecessary treatment. This study aimed to explore the effect of an antibiotic...
8.
Huang C, Lee S, Wei T, Kuo Y, Wu S, Ku H
Biomed Pharmacother . 2021 Aug; 142:112028. PMID: 34399201
Acute kidney disease due to renal ischemia/reperfusion (I/R) is a major clinical problem without effective therapies. The injured tubular epithelial cells may undergo epithelial-mesenchymal transition (EMT). It will loss epithelial...
9.
Weng Y, Liang C, Tseng C, Lee S, Yeh G
Medicine (Baltimore) . 2021 Aug; 100(29):e26675. PMID: 34398035
Population aging and air pollution are global concerns. The purpose of this study is to explore the relationship among particulate matter with a diameter of 2.5 μm or less (PM2.5)...
10.
Lee S, Chien D, Hung S, Ku H
J Formos Med Assoc . 2020 Dec; 120(3):1043-1044. PMID: 33281017
No abstract available.