Shih-Queen Lee-Lin
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Explore the profile of Shih-Queen Lee-Lin including associated specialties, affiliations and a list of published articles.
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12
Citations
799
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Recent Articles
1.
Joglekar P, Conlan S, Lee-Lin S, Deming C, Saheb Kashaf S, Kong H, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(47):e2310585120.
PMID: 37956283
Human skin is stably colonized by a distinct microbiota that functions together with epidermal cells to maintain a protective physical barrier. , a prominent genus of the skin microbiota, participates...
2.
Joglekar P, Conlan S, Lee-Lin S, Deming C, Saheb Kashaf S, Kong H, et al.
bioRxiv
. 2023 Jul;
PMID: 37503282
Human skin is stably colonized by a distinct microbiota that functions together with epidermal cells to maintain a protective physical barrier. , a prominent genus of the skin microbiota, participates...
3.
Tirosh O, Conlan S, Deming C, Lee-Lin S, Huang X, Su H, et al.
Nat Med
. 2018 Nov;
24(12):1815-1821.
PMID: 30397357
Human microbiome studies have revealed the intricate interplay of host immunity and bacterial communities to achieve homeostatic balance. Healthy skin microbial communities are dominated by bacteria with low viral representation,...
4.
Unni A, Lockwood W, Zejnullahu K, Lee-Lin S, Varmus H
Elife
. 2015 Jun;
4:e06907.
PMID: 26047463
Human lung adenocarcinomas (LUAD) contain mutations in EGFR in ∼15% of cases and in KRAS in ∼30%, yet no individual adenocarcinoma appears to carry activating mutations in both genes, a...
5.
Sen S, Barb J, Cherukuri P, Accame D, Elkahloun A, Singh L, et al.
BMC Genomics
. 2014 Mar;
15:198.
PMID: 24628908
Background: Massively-parallel cDNA sequencing (RNA-Seq) is a new technique that holds great promise for cardiovascular genomics. Here, we used RNA-Seq to study the transcriptomes of matched coronary artery disease cases...
6.
Andres A, Dennis M, Kretzschmar W, Cannons J, Lee-Lin S, Hurle B, et al.
PLoS Genet
. 2010 Oct;
6(10):e1001157.
PMID: 20976248
A remarkable characteristic of the human major histocompatibility complex (MHC) is its extreme genetic diversity, which is maintained by balancing selection. In fact, the MHC complex remains one of the...
7.
Antonellis A, Huynh J, Lee-Lin S, Vinton R, Renaud G, Loftus S, et al.
PLoS Genet
. 2008 Sep;
4(9):e1000174.
PMID: 18773071
Sox10 is a dynamically regulated transcription factor gene that is essential for the development of neural crest-derived and oligodendroglial populations. Developmental genes often require multiple regulatory sequences that integrate discrete...
8.
Antonellis A, Lee-Lin S, Wasterlain A, Leo P, Quezado M, Goldfarb L, et al.
J Neurosci
. 2006 Oct;
26(41):10397-406.
PMID: 17035524
Charcot-Marie-Tooth disease type 2D (CMT2D) and distal spinal muscular atrophy type V (dSMA-V) are axonal neuropathies characterized by a phenotype that is more severe in the upper extremities. We previously...
9.
Antonellis A, Bennett W, Menheniott T, Prasad A, Lee-Lin S, Green E, et al.
Hum Mol Genet
. 2005 Dec;
15(2):259-71.
PMID: 16330480
The transcription factor SOX10 is mutated in the human neurocristopathy Waardenburg-Shah syndrome (WS4), which is characterized by enteric aganglionosis and pigmentation defects. SOX10 directly regulates genes expressed in neural crest...
10.
Antonellis A, Ellsworth R, Sambuughin N, Puls I, Abel A, Lee-Lin S, et al.
Am J Hum Genet
. 2003 Apr;
72(5):1293-9.
PMID: 12690580
Charcot-Marie-Tooth disease type 2D (CMT2D) and distal spinal muscular atrophy type V (dSMA-V) are axonal peripheral neuropathies inherited in an autosomal dominant fashion. Our previous genetic and physical mapping efforts...