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Shigeyuki Takeshita

Explore the profile of Shigeyuki Takeshita including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 133
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Recent Articles
1.
Araki T, Hayashi K, Shimokawa M, Otsuka T, Sonoda Y, Honda T, et al.
Ther Adv Med Oncol . 2025 Feb; 17:17588359251320768. PMID: 39990012
Background: Relationships between cancer onset, progression, and inflammation have been reported; yet, the significance of inflammatory markers before and after treatment with nanoliposomal irinotecan and fluorouracil with folic acid (NFF)...
2.
Araki T, Sonoda Y, Shimokawa M, Otsuka T, Hayashi K, Honda T, et al.
Sci Rep . 2025 Jan; 15(1):3427. PMID: 39870769
The relationship between nanoliposomal irinotecan/fluorouracil/leucovorin (NFF) treatment outcomes and neutropenia in patients with pancreatic cancer has not been thoroughly examined. Thus, we conducted a retrospective analysis of data from patients...
3.
Araki T, Kawahira M, Shimokawa M, Otsuka T, Hayashi K, Sonoda Y, et al.
Oncology . 2024 Oct; :1-11. PMID: 39427640
Introduction: Fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) improve overall survival (OS) and progression-free survival (PFS) in patients with pancreatic cancer, compared with gemcitabine (GEM). However, whether PFS is a surrogate...
4.
Shibuki T, Otsuka T, Shimokawa M, Nakazawa J, Arima S, Fukahori M, et al.
Sci Rep . 2024 Jul; 14(1):16906. PMID: 39043707
This study aimed to compare second-line treatment outcomes for patients with unresectable pancreatic cancer previously treated with gemcitabine plus nab-paclitaxel (GnP) therapy. We conducted an integrated analysis of two retrospective...
5.
Kodama T, Imajima T, Shimokawa M, Otsuka T, Kawahira M, Nakazawa J, et al.
Sci Rep . 2024 May; 14(1):12422. PMID: 38816500
Nanoliposomal irinotecan with fluorouracil and folinic acid (NFF) is a standard regimen after gemcitabine-based therapy for patients with unresectable or recurrent pancreatic cancer. However, there are limited clinical data on...
6.
Araki T, Takeshita S, Kawasaki H, Kusumoto K, Ohata K, Shigematsu K, et al.
Intern Med . 2018 Aug; 58(2):195-199. PMID: 30146582
A 57-year-old woman was admitted with lower abdominal pain and bloody bowel discharge. She was diagnosed with rectal tumor by colonoscopy, and a biopsy was performed. Surgery was performed, resulting...
7.
Akiyoshi K, Hamaguchi T, Yoshimura K, Takahashi N, Honma Y, Iwasa S, et al.
Clin Colorectal Cancer . 2017 Nov; 17(1):e83-e89. PMID: 29169974
Background: In some recently updated clinical guidelines, the fully humanized monoclonal antibody panitumumab, combined with irinotecan, has been recommended as an optional third-line chemotherapy for KRAS wild-type metastatic colorectal cancer...
8.
Miyaaki H, Ichikawa T, Nakao K, Takeshita S, Shibata H, Ozawa E, et al.
Clin J Gastroenterol . 2015 Jul; 2(3):218-221. PMID: 26192300
A 60-year-old man with alcoholic liver cirrhosis was admitted to our hospital with severe anemia and tarry stool. Upper gastrointestinal endoscopy revealed grade 4 esophageal varices without bleeding and severe...
9.
Hino N, Matsuzaki T, Komatsu N, Akiyama M, Ozawa E, Miuma S, et al.
Nihon Shokakibyo Gakkai Zasshi . 2013 Jun; 110(6):1038-43. PMID: 23739737
A 55-year-old woman was admitted to our hospital because of diverse symptoms of portal hypertension, such as refractory ascites, diarrhea, and general malaise. Blood test revealed liver and renal dysfunction...
10.
Miuma S, Ichikawa T, Arima K, Takeshita S, Muraoka T, Matsuzaki T, et al.
J Cell Biochem . 2012 May; 113(10):3113-21. PMID: 22581719
Abnormal sugar metabolism is closely related to chronic liver diseases, including hepatocellular carcinoma (HCC). We previously reported that fasting hyperinsulinemia is a poor prognostic factor for HCC patients. A recent...