Shigeru Hirano
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Explore the profile of Shigeru Hirano including associated specialties, affiliations and a list of published articles.
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199
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1875
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Recent Articles
1.
Nakagawa Y, Kaneko M, Sugiyama Y, Nonaka K, Mukudai S, Hirano S
J Voice
. 2025 Feb;
PMID: 39971672
Objective: Hoarseness is often observed in patients with acute central nervous system (CNS) impairment. However, the vocal function is not routinely assessed. The purpose of this prospective study was to...
2.
Fuse S, Sugiyama Y, Dhingra R, Hirano S, Dutschmann M, Okada Y, et al.
Pflugers Arch
. 2025 Jan;
PMID: 39862246
The nucleus tractus solitarius (NTS) contains neurons that relay sensory swallowing commands information from the oropharyngeal cavity and swallowing premotor neurons of the dorsal swallowing group (DSG). However, the spatio-temporal...
3.
Suzuki K, Fumino S, Iguchi M, Takayama S, Kim K, Hirano S, et al.
Pediatr Surg Int
. 2024 Dec;
41(1):35.
PMID: 39699633
Purpose: The study reviewed a multidisciplinary approach to treating cervicofacial lymphatic malformations (CFLMs) in children. Methods: Between 2007 and 2023, 53 children with CFLMs were treated with the median on-set...
4.
Okamoto S, Yasuda M, Kawaguchi K, Yasuoka K, Kikukawa Y, Asano S, et al.
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201753
An application of CO/HCO-free solution (Zero-CO) did not increase intracellular pH (pH) in ciliated human nasal epithelial cells (c-hNECs), leading to no increase in frequency (CBF) or amplitude (CBA) of...
5.
Tsujikawa T, Ohno K, Morita K, Saburi S, Mitsuda J, Yoshimura K, et al.
Front Immunol
. 2024 Aug;
15:1390873.
PMID: 39136017
Background: In view of improving biomarkers predicting the efficacy of immunotherapy for head and neck squamous cell carcinoma (R/M HNSCC), this multicenter retrospective study aimed to identify clinical, tumor microenvironmental,...
6.
Kimura A, Tsujikawa T, Morimoto H, Saburi S, Mitsuda J, Mukudai S, et al.
Heliyon
. 2024 Jul;
10(13):e33830.
PMID: 39050465
Intratumoral immune profiles are related to prognosis and therapeutic efficacy, and could result in personalized treatments based on biomarkers. To develop a multiplex, quantitative, and rapid tissue evaluation method based...
7.
Hashimoto K, Sugiyama Y, Kaneko M, Kinoshita S, Yamamoto R, Ishida T, et al.
Front Neurol
. 2024 Jul;
15:1401982.
PMID: 38962483
Introduction: Swallowing impairment is a crucial issue that can lead to aspiration, pneumonia, and malnutrition. Animal models are useful to reveal pathophysiology and to facilitate development of new treatments for...
8.
Matsushita H, Mukudai S, Hashimoto K, Kaneko M, Sugiyama Y, Branski R, et al.
Laryngoscope
. 2024 Jun;
134(11):4593-4598.
PMID: 38860441
Objectives: Vocal fold scar remains a therapeutic challenge. Vocal fold fibroblasts (VFFs) secrete extracellular matrix (ECM), and transforming growth factor-beta 1 (TGF-β1)-mediated fibroblast to myofibroblast differentiation is central to the...
9.
Hara M, Saburi S, Uehara N, Tsujikawa T, Kubo M, Furukawa T, et al.
Cancers (Basel)
. 2024 Apr;
16(7).
PMID: 38611038
Background: The goal of this study was to evaluate the antitumor immune effects of B7-1 gene expression in addition to immune checkpoint inhibitor against squamous cell carcinoma. Methods: A murine...
10.
Hirano S, Inufusa H, You F
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38473848
The vocal fold vibrates in high frequency to create voice sound. The vocal fold has a sophisticated histological "layered structure" that enables such vibration. As the vibration causes fricative damage...