Shervin Tabrizi
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Explore the profile of Shervin Tabrizi including associated specialties, affiliations and a list of published articles.
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24
Citations
1096
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Recent Articles
1.
Sim E, Rhoades J, Xiong K, Walsh L, Crnjac A, Blewett T, et al.
medRxiv
. 2025 Feb;
PMID: 39974077
Purpose: While circulating tumor DNA (ctDNA) is a promising biomarker for minimal residual disease (MRD) detection in head and neck squamous cell carcinoma (HNSCC), more sensitive assays are needed for...
2.
Tabrizi S, Martin-Alonso C, Xiong K, Bhatia S, Adalsteinsson V, Love J
Trends Cell Biol
. 2024 Dec;
PMID: 39730275
Technical advances over the past two decades have enabled robust detection of cell-free DNA (cfDNA) in biological samples. Yet, higher clinical sensitivity is required to realize the full potential of...
3.
Kotliar D, Raju S, Tabrizi S, Odia I, Goba A, Momoh M, et al.
Nat Microbiol
. 2024 Feb;
9(3):751-762.
PMID: 38326571
Infection with Lassa virus (LASV) can cause Lassa fever, a haemorrhagic illness with an estimated fatality rate of 29.7%, but causes no or mild symptoms in many individuals. Here, to...
4.
Martin-Alonso C, Tabrizi S, Xiong K, Blewett T, Sridhar S, Crnjac A, et al.
Science
. 2024 Jan;
383(6680):eadf2341.
PMID: 38236959
Liquid biopsies enable early detection and monitoring of diseases such as cancer, but their sensitivity remains limited by the scarcity of analytes such as cell-free DNA (cfDNA) in blood. Improvements...
5.
Brastianos P, Twohy E, Geyer S, Gerstner E, Kaufmann T, Tabrizi S, et al.
N Engl J Med
. 2023 Jul;
389(2):118-126.
PMID: 37437144
Background: Craniopharyngiomas, primary brain tumors of the pituitary-hypothalamic axis, can cause clinically significant sequelae. Treatment with the use of surgery, radiation, or both is often associated with substantial morbidity related...
6.
Bae J, Liu R, Roberts E, Nguyen E, Tabrizi S, Rhoades J, et al.
Nat Genet
. 2023 Apr;
55(5):871-879.
PMID: 37106072
Detecting mutations from single DNA molecules is crucial in many fields but challenging. Next-generation sequencing (NGS) affords tremendous throughput but cannot directly sequence double-stranded DNA molecules ('single duplexes') to discern...
7.
Martin-Alonso C, Tabrizi S, Xiong K, Blewett T, Patel S, An Z, et al.
bioRxiv
. 2023 Jan;
PMID: 36711603
Liquid biopsies are enabling minimally invasive monitoring and molecular profiling of diseases across medicine, but their sensitivity remains limited by the scarcity of cell-free DNA (cfDNA) in blood. Here, we...
8.
Tabrizi S, Martin-Alonso C, Xiong K, Blewett T, Sridhar S, An Z, et al.
bioRxiv
. 2023 Jan;
PMID: 36711455
Blood-based, or "liquid," biopsies enable minimally invasive diagnostics but have limits on sensitivity due to scarce cell-free DNA (cfDNA). Improvements to sensitivity have primarily relied on enhancing sequencing technology ....
9.
Ho A, Tabrizi S, Dunn S, McArthur H
Breast Cancer Res Treat
. 2021 Oct;
191(2):229-241.
PMID: 34714450
Purpose: Immune checkpoint inhibition (ICI) has demonstrated clinically significant efficacy when combined with chemotherapy in triple negative breast cancer (TNBC). Although many patients derived benefit, others do not respond to...
10.
Tabrizi S, Trippa L, Cagney D, Aizer A, Tanguturi S, Ventz S, et al.
JAMA Netw Open
. 2021 Mar;
4(3):e213304.
PMID: 33779742
Importance: During the COVID-19 pandemic, cancer therapy may put patients at risk of SARS-CoV-2 infection and mortality. The impacts of proposed alternatives on reducing infection risk are unknown. Objective: To...