Sheng-Hung Liu
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Explore the profile of Sheng-Hung Liu including associated specialties, affiliations and a list of published articles.
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6
Citations
72
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Recent Articles
1.
Liao H, Chou Y, Lin C, Liu S, Oswita A, Huang Y, et al.
Biochem Pharmacol
. 2019 Mar;
163:308-320.
PMID: 30822403
Chronic myelogenous leukemia (CML) is clinically treated with imatinib, which inhibits the kinase activity of the Bcr-Abl oncoprotein. However, imatinib resistance remains a common clinical issue. Andrographolide, the major compound...
2.
Hsu M, Liu S, Wang C, Hu N, Wu E, Shih Y, et al.
Eur J Pharmacol
. 2017 Jul;
812:113-120.
PMID: 28694068
Con A-induced hepatitis in mice is an established model of autoimmune hepatitis (AIH). JKB-122, a toll-like receptor 4 (TLR4) antagonist, was tested for hepatotprotectant activity. Within several hours of Con...
3.
Hsu Y, Hsu Y, Liu S, Liao H, Lee P, Lin C, et al.
PLoS One
. 2016 Apr;
11(4):e0152770.
PMID: 27035713
Andrographolide (ANDRO) is a lactone diterpenoid compound present in the medicinal plant Andrographis paniculata which is clinically applied for multiple human diseases in Asia and Europe. The pharmacological activities of...
4.
Fu S, Lin C, Hsu M, Liu S, Huang Y, Chen Y
Oncotarget
. 2016 Feb;
7(10):11677-86.
PMID: 26883191
CCL-34, a synthetic α-galactosylceramide analog, has been reported as an activator of toll-like receptor 4 (TLR4) in macrophages. TLR4 is highly expressed in dendritic cell (DC) and several TLR4 agonists...
5.
Liu S, Lin C, Liang F, Chen P, Kuo C, Alam M, et al.
Biochem Pharmacol
. 2013 Oct;
87(2):229-42.
PMID: 24161787
Andrographolide is a diterpenoid compound isolated from Andrographis paniculata that exhibits anticancer activity. We previously reported that andrographolide suppressed v-Src-mediated cellular transformation by promoting the degradation of Src. In the...
6.
Liu S, Lin C, Hung S, Chou J, Chi C, Fu S
J Agric Food Chem
. 2010 Oct;
58(20):10831-9.
PMID: 20923145
Macrophages and dendritic cells are required for initiating innate immunity and adaptive immunity. Aberrant activation of macrophages and dendritic cells can cause detrimental immune responses; thus, agents effectively modulating their...