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Sheng-Feng Tsai

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Articles 33
Citations 389
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Recent Articles
1.
Huang C, Tsai S, Liu S, Yeh M, Hung H, Lee C, et al.
J Inflamm Res . 2024 Nov; 17:7993-8008. PMID: 39507265
Introduction: Insulin, the key hormone for glucose regulation, has garnered attention for its role as an immune modulator. Impaired insulin signaling in the central nervous system is linked to neuroinflammation...
2.
Tsai S, Hsu P, Yeh M, Hung H, Shih M, Chung B, et al.
Biomed J . 2024 Jul; :100772. PMID: 39048079
Background: This study was designed to examine how glucocorticoids (GCs) induced by a long-term ingestion of high-fat diet (HFD) mediate the HFD-induced adipose expansion and obesity. Material And Methods: To...
3.
Tsai S, Kuo Y
J Physiol Investig . 2024 May; 67(1):3-14. PMID: 38780268
Oxytocin (OXT), a neuropeptide originating from the hypothalamus and traditionally associated with peripheral functions in parturition and lactation, has emerged as a pivotal player in the central regulation of the...
4.
Huang H, Hsu P, Tsai S, Chuang Y, Chen D, Xu G, et al.
Adv Sci (Weinh) . 2023 Nov; 10(35):e2302345. PMID: 37964413
Although the relationships of cerebrovascular hemodynamic dysfunction with neurodegenerative diseases remain unclear, many studies have indicated that poor cerebral perfusion accelerates the progression of neurodegenerative diseases, such as Alzheimer's disease...
5.
Hung H, Tsai S, Chou H, Tsai M, Hsu P, Kuo Y
Sci Rep . 2023 Apr; 13(1):5511. PMID: 37016048
Monocytes are a major population of circulating immune cells that play a crucial role in producing pro-inflammatory cytokines in the body. The actions of monocytes are known to be influenced...
6.
Tsai S, Hsu P, Chen Y, Hossain M, Chen P, Tzeng S, et al.
Mol Psychiatry . 2022 Sep; 27(11):4372-4384. PMID: 36180573
Comorbidity exists between metabolic disorders and depressive syndrome with unclear mechanisms. To characterize the causal relationship, we adopted a 12-week high-fat diet (HFD) to induce metabolic disorder and depressive phenotypes...
7.
Hung H, Tsai S, Sie S, Kuo Y
Immun Inflamm Dis . 2022 Apr; 10(5):e610. PMID: 35478445
Introduction: Diabetes mellitus emerges as a global health crisis and is related to the development of neurodegenerative diseases. Microglia, a population of macrophages-like cells, govern immune defense in the central...
8.
Wang T, Wu S, Pan B, Tsai S, Kuo Y
Cells . 2022 Feb; 11(3). PMID: 35159290
Parkinson's disease (PD) is an age-related neurodegenerative disease caused by a selective loss of dopaminergic (DA) neurons in the substantia nigra (SN). Microglial activation is implicated in the pathogenesis of...
9.
Tsai S, Hung H, Shih M, Chang F, Chung B, Wang C, et al.
FASEB J . 2021 Dec; 36(1):e22130. PMID: 34959259
This study aimed to investigate the causal relationship between chronic ingestion of a high-fat diet (HFD)-induced secretion of glucocorticoids (GCs) and the development of non-alcoholic fatty liver disease (NAFLD). We...
10.
Tzu-Feng Wang T, Tsai S, Zhao Z, Shih M, Wang C, Yang T, et al.
Chin J Physiol . 2021 Sep; 64(4):186-193. PMID: 34472449
Adult hippocampal neurogenesis (AHN) is suppressed by chronic stress. The negative effect of stress is mainly attributed to increased levels of stress hormones (e.g. glucocorticoids, GCs). Exercise enhances AHN, yet...