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Sheli L Ostrow

Explore the profile of Sheli L Ostrow including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 67
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Recent Articles
1.
Ostrow S, Hershberg R
Genome Biol Evol . 2016 May; 8(5):1614-20. PMID: 27190005
Cancer is special among genetic disorders in two major ways: first, cancer is a disease of the most basic of cellular functions, such as cell proliferation, differentiation, and the maintenance...
2.
Ostrow S, Simon E, Prinz E, Bick T, Shentzer T, Nagawkar S, et al.
Sci Rep . 2016 Feb; 6:21927. PMID: 26902163
Different tumor types vary greatly in their distribution of driver substitutions. Here, we analyzed how mutation and natural selection contribute to differences in the distribution of KRAS driver substitutions between...
3.
Ostrow S, Barshir R, DeGregori J, Yeger-Lotem E, Hershberg R
PLoS Genet . 2014 Mar; 10(3):e1004239. PMID: 24603726
Cancer is an evolutionary process in which cells acquire new transformative, proliferative and metastatic capabilities. A full understanding of cancer requires learning the dynamics of the cancer evolutionary process. We...