Shelby Winans
Overview
Explore the profile of Shelby Winans including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
74
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0
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Recent Articles
1.
Winans S, Yu H, de Los Santos K, Wang G, KewalRamani V, Goff S
Nat Commun
. 2022 Mar;
13(1):1474.
PMID: 35304442
Retroviruses utilize the viral integrase (IN) protein to integrate a DNA copy of their genome into host chromosomal DNA. HIV-1 integration sites are highly biased towards actively transcribed genes, likely...
2.
Winans S, Goff S
PLoS Pathog
. 2020 Dec;
16(12):e1009147.
PMID: 33351861
The central function of the retroviral integrase protein (IN) is to catalyze the integration of viral DNA into the host genome to form the provirus. The IN protein has also...
3.
Winans S, Beemon K
Cell Host Microbe
. 2019 Aug;
26(2):154-155.
PMID: 31415745
In this issue of Cell Host & Microbe, Courtney et al. (2019a) find that HIV-1 genomic RNA has much more mC than cellular mRNA. Deleting the m5C "writer" NSUN2 decreases...
4.
Malhotra S, Winans S, Lam G, Justice J, Morgan R, Beemon K
PLoS Pathog
. 2017 Nov;
13(11):e1006708.
PMID: 29099869
Avian leukosis virus (ALV) is a simple retrovirus that causes a wide range of tumors in chickens, the most common of which are B-cell lymphomas. The viral genome integrates into...
5.
Winans S, Flynn A, Malhotra S, Balagopal V, Beemon K
Oncotarget
. 2017 Sep;
8(34):57302-57315.
PMID: 28915671
Avian leukosis virus induces tumors in chickens by integrating into the genome and altering expression of nearby genes. Thus, ALV can be used as an insertional mutagenesis tool to identify...
6.
Winans S, Larue R, Abraham C, Shkriabai N, Skopp A, Winkler D, et al.
J Virol
. 2017 Jan;
91(7).
PMID: 28122976
All retroviruses need to integrate a DNA copy of their genome into the host chromatin. Cellular proteins regulating and targeting lentiviral and gammaretroviral integration in infected cells have been discovered,...
7.
Nehyba J, Malhotra S, Winans S, OHare T, Justice 4th J, Beemon K
J Virol
. 2016 Aug;
90(20):9509-17.
PMID: 27512065
Unlabelled: Avian leukosis virus (ALV) induces tumors by integrating its proviral DNA into the chicken genome and altering the expression of nearby genes via strong promoter and enhancer elements. Viral...