Sheila Le
Overview
Explore the profile of Sheila Le including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
196
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Recent Articles
1.
Retraction Notice to: NPTX1 Regulates Neural Lineage Specification from Human Pluripotent Stem Cells
Boles N, Hirsch S, Le S, Corneo B, Najm F, Minotti A, et al.
Cell Rep
. 2023 Dec;
43(1):113625.
PMID: 38127623
No abstract available.
2.
Boles N, Hirsch S, Le S, Corneo B, Najm F, Minotti A, et al.
Cell Rep
. 2014 Feb;
6(4):724-36.
PMID: 24529709
Neural induction is the first fundamental step in nervous system formation. During development, a tightly regulated niche modulates transient extracellular signals to influence neural lineage commitment. To date, however, the...
3.
Lotz S, Goderie S, Tokas N, Hirsch S, Ahmad F, Corneo B, et al.
PLoS One
. 2013 Feb;
8(2):e56289.
PMID: 23437109
An essential aspect of stem cell culture is the successful maintenance of the undifferentiated state. Many types of stem cells are FGF2 dependent, and pluripotent stem cells are maintained by...
4.
Surolia I, Pirnie S, Chellappa V, Taylor K, Cariappa A, Moya J, et al.
Nature
. 2010 Jun;
466(7303):243-7.
PMID: 20555325
Sialic acid acetylesterase (SIAE) is an enzyme that negatively regulates B lymphocyte antigen receptor signalling and is required for the maintenance of immunological tolerance in mice. Heterozygous loss-of-function germline rare...
5.
Rothenberg S, Engelman J, Le S, Riese 2nd D, Haber D, Settleman J
Proc Natl Acad Sci U S A
. 2008 Aug;
105(34):12480-4.
PMID: 18711136
The clinical efficacy of selective kinase inhibitors suggests that some cancer cells may become dependent on a single oncogene for survival. RNAi has been increasingly used to understand such "oncogene...