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Sheelu Monga

Explore the profile of Sheelu Monga including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 8
Citations 46
Followers 0
Related Specialties
Biochemistry
Cell Biology
Molecular Biology
Top 10 Co-Authors
Moshe Gavish
Abraham Weizman
Meygal Kahana
Valentino Laquintana
Rami Yashaev
Nunzio Denora
Rula Amara
Rafi Nagler
Syed Mushfiqur Rahman
Sukhdev Singh
Published In
Cells
Biology (Basel)
J Fungi (Basel)
Biomolecules
Brain Behav Immun Health
Affiliations
Soon will be listed here.
Recent Articles
1.
Novel TSPO Ligand 2-Cl-MGV-1 Can Counteract Lipopolysaccharide Induced Inflammatory Response in Murine RAW264.7 Macrophage Cell Line and Lung Models
Obeid F, Kahana M, Dahle B, Monga S, Zohar Y, Weizman A, et al.
Cells . 2024 Oct; 13(20. PMID: 39451220
We assessed the anti-inflammatory activity of the TSPO ligand 2-Cl-MGV-1. Lipopolysaccharide (LPS) was used to induce inflammatory response in a murine RAW264.7 macrophage model (LPS: 100 ng/mL) and a mouse...
2.
Iron overload induces cerebral endothelial senescence in aged mice and in primary culture in a sex-dependent manner
Noh B, Blasco-Conesa M, Rahman S, Monga S, Ritzel R, Guzman G, et al.
Aging Cell . 2023 Sep; 22(11):e13977. PMID: 37675802
Iron imbalance in the brain negatively affects brain function. With aging, iron levels increase in the brain and contribute to brain damage and neurological disorders. Changes in the cerebral vasculature...
3.
The Effect of the Classical TSPO Ligand PK 11195 on In Vitro Cobalt Chloride Model of Hypoxia-like Condition in Lung and Brain Cell Lines
Amara R, Zeineh N, Monga S, Weizman A, Gavish M
Biomolecules . 2022 Oct; 12(10). PMID: 36291606
The mitochondrial translocator protein (TSPO) is a modulator of the apoptotic pathway involving reactive oxygen species (ROS) generation, mitochondrial membrane potential (Δψm) collapse, activation of caspases, and eventually initiation of...
4.
The Effect of Natural-Based Formulation (NBF) on the Response of RAW264.7 Macrophages to LPS as an In Vitro Model of Inflammation
Monga S, Fares B, Yashaev R, Melamed D, Kahana M, Fares F, et al.
J Fungi (Basel) . 2022 Mar; 8(3). PMID: 35330323
Macrophages are some of the most important immune cells in the organism and are responsible for creating an inflammatory immune response in order to inhibit the passage of microscopic foreign...
5.
The Neuro-Protective Effects of the TSPO Ligands CB86 and CB204 on 6-OHDA-Induced PC12 Cell Death as an In Vitro Model for Parkinson's Disease
Monga S, Denora N, Laquintana V, Yashaev R, Weizman A, Gavish M
Biology (Basel) . 2021 Nov; 10(11). PMID: 34827176
Parkinson's disease (PD) is a progressive neurodegenerative disorder which is characterized by the degeneration of dopaminergic neurons in substantia nigra (SN). Oxidative stress or reactive oxygen species (ROS) generation was...
6.
The protective effect of the TSPO ligands 2,4-Di-Cl-MGV-1, CB86, and CB204 against LPS-induced M1 pro-inflammatory activation of microglia
Monga S, Denora N, Laquintana V, Franco M, Marek I, Singh S, et al.
Brain Behav Immun Health . 2021 Sep; 5:100083. PMID: 34589858
We have shown previously, that the 18 ​kDa translocator protein (TSPO) synthetic ligands quinazoline derivatives (2-Cl-MGV-1 and MGV-1) can inhibit activation of in BV-2 microglial cells. In the present study...
7.
The Efficacy of the Novel TSPO Ligands 2-Cl-MGV-1 and 2,4-Di-Cl-MGV-1 Compared to the Classical TSPO Ligand PK 11195 to Counteract the Release of Chemokines from LPS-Stimulated BV-2 Microglial Cells
Monga S, Weizman A, Gavish M
Biology (Basel) . 2020 Sep; 9(9). PMID: 32938018
The impact of ligands of the 18 kDa translocator protein (TSPO) on the release of chemokines is not vastly investigated. In the present study, we assessed the effect of our...
8.
Inhibitory Effects of the Two Novel TSPO Ligands 2-Cl-MGV-1 and MGV-1 on LPS-induced Microglial Activation
Monga S, Nagler R, Amara R, Weizman A, Gavish M
Cells . 2019 May; 8(5). PMID: 31121852
The 18 kDa translocator protein (TSPO) ligands 2-Cl-MGV-1 and MGV-1 can attenuate cell death of astrocyte-like cells (U118MG) and induce differentiation of neuronal progenitor cells (PC-12). Lipopolysaccharide (LPS) is a...