She-Juan An
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Explore the profile of She-Juan An including associated specialties, affiliations and a list of published articles.
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37
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1084
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Recent Articles
1.
Blechter B, Hsiung C, Wang X, Zhang H, Seow W, Shi J, et al.
J Thorac Oncol
. 2024 Nov;
PMID: 39581378
We assessed the association between a genome-wide polygenic risk score (PRS) developed for lung adenocarcinoma (LUAD) risk and mutation on the EGFR gene in 998 East Asian never-smoking female LUAD...
2.
Blechter B, Wang X, Shi J, Shiraishi K, Choi J, Matsuo K, et al.
medRxiv
. 2024 Jul;
PMID: 38978671
Polygenic risk scores (PRSs) are promising for risk stratification but have mainly been developed in European populations. This study developed single- and multi-ancestry PRSs for lung adenocarcinoma (LUAD) in East...
3.
Shi J, Shiraishi K, Choi J, Matsuo K, Chen T, Dai J, et al.
Nat Commun
. 2023 May;
14(1):3043.
PMID: 37236969
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study...
4.
Wong J, Zhang H, Hsiung C, Shiraishi K, Yu K, Matsuo K, et al.
Genomics
. 2019 Jul;
112(2):1223-1232.
PMID: 31306748
We investigated whether genetic susceptibility to tuberculosis (TB) influences lung adenocarcinoma development among never-smokers using TB genome-wide association study (GWAS) results within the Female Lung Cancer Consortium in Asia. Pathway...
5.
Yin Z, Tu H, Fu M, Zhong W, An S, Yan H, et al.
J Cancer
. 2018 Sep;
9(17):2987-2993.
PMID: 30210620
Clinical studies have confirmed epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) used in lung cancer patients with mutations can obtain a better result, but still part of the patients...
6.
Seow W, Matsuo K, Hsiung C, Shiraishi K, Song M, Kim H, et al.
Hum Mol Genet
. 2016 Dec;
26(2):454-465.
PMID: 28025329
To evaluate associations by EGFR mutation status for lung adenocarcinoma risk among never-smoking Asian women, we conducted a meta-analysis of 11 loci previously identified in genome-wide association studies (GWAS). Genotyping...
7.
Bai X, Zhang X, Yang S, An S, Chen Z, Su J, et al.
PLoS One
. 2016 Mar;
11(3):e0149370.
PMID: 26943330
Aberrant activation of the hedgehog (Hh) signaling pathway has been implicated in the epithelial-to-mesenchymal transition (EMT) and cancer stem-like cell (CSC) maintenance; both processes can result in tumor progression and...
8.
Wang Z, Seow W, Shiraishi K, Hsiung C, Matsuo K, Liu J, et al.
Hum Mol Genet
. 2016 Jan;
25(3):620-9.
PMID: 26732429
Genome-wide association studies (GWAS) of lung cancer in Asian never-smoking women have previously identified six susceptibility loci associated with lung cancer risk. To further discover new susceptibility loci, we imputed...
9.
Han J, An S, Su W, Chen Z, Su J, Yan H, et al.
Int J Biol Markers
. 2015 Dec;
31(2):e144-52.
PMID: 26689248
Background: Our previous study identified rs9387478 as a new susceptibility locus associated with lung cancer in never-smoking women in Asia; however, the clinical and prognostic significance of this finding is...
10.
Sampson J, Wheeler W, Yeager M, Panagiotou O, Wang Z, Berndt S, et al.
J Natl Cancer Inst
. 2015 Oct;
107(12):djv279.
PMID: 26464424
Background: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide...