Shawn M Ren
Overview
Explore the profile of Shawn M Ren including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
172
Followers
0
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Recent Articles
1.
Amen A, Fellmann C, Soczek K, Ren S, Lew R, Knott G, et al.
Proc Natl Acad Sci U S A
. 2021 Mar;
118(13).
PMID: 33758097
Most glioblastomas (GBMs) achieve cellular immortality by acquiring a mutation in the telomerase reverse transcriptase () promoter. promoter mutations create a binding site for a GA binding protein (GABP) transcription...
2.
Oakes B, Fellmann C, Rishi H, Taylor K, Ren S, Nadler D, et al.
Cell
. 2019 Jan;
176(1-2):254-267.e16.
PMID: 30633905
The ability to engineer natural proteins is pivotal to a future, pragmatic biology. CRISPR proteins have revolutionized genome modification, yet the CRISPR-Cas9 scaffold is not ideal for fusions or activation...
3.
Watters K, Fellmann C, Bai H, Ren S, Doudna J
Science
. 2018 Sep;
362(6411):236-239.
PMID: 30190307
Cas12a (Cpf1) is a CRISPR-associated nuclease with broad utility for synthetic genome engineering, agricultural genomics, and biomedical applications. Although bacteria harboring CRISPR-Cas9 or CRISPR-Cas3 adaptive immune systems sometimes acquire mobile...