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Shashi B Pandit

Explore the profile of Shashi B Pandit including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 154
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Recent Articles
1.
Verma P, Thakur D, Pandit S
Bioinform Adv . 2024 Nov; 4(1):vbae157. PMID: 39569321
Motivation: Gene transcripts are distinguished by the composition of their exons, and this different exon composition may contribute to advancing proteome complexity. Despite the availability of alternative splicing information documented...
2.
Verma P, Panda B, Singh K, Pandit S
ACS Biomater Sci Eng . 2021 Jun; 7(7):3156-3165. PMID: 34151552
The excellent mechanical strength and toughness of spider silk are well characterized experimentally and understood atomistically using computational simulations. However, little attention has been focused on understanding whether the amino...
3.
Tayal N, Choudhary P, Pandit S, Sandhu K
Mol Biosyst . 2014 Mar; 10(6):1469-80. PMID: 24668165
Despite recent advances, it is yet not clear how intrinsically disordered regions in proteins recognize their targets without any defined structures. Short linear motifs had been proposed to mediate molecular...
4.
Carbonell P, Fichera D, Pandit S, Faulon J
BMC Syst Biol . 2012 Feb; 6:10. PMID: 22309974
Background: We consider the possibility of engineering metabolic pathways in a chassis organism in order to synthesize novel target compounds that are heterologous to the chassis. For this purpose, we...
5.
Pandit S, Skolnick J
Proteins . 2010 Jul; 78(13):2769-80. PMID: 20635423
In a variety of threading methods, often poorly ranked (low z-score) templates have good alignments. Here, a new method, TASSER_low-zsc that identifies these low z-score-ranked templates to improve protein structure...
6.
Pandit S, Brylinski M, Zhou H, Gao M, Arakaki A, Skolnick J
Bioinformatics . 2010 Jan; 26(5):687-8. PMID: 20080513
Unlabelled: In the post-genomic era, the annotation of protein function facilitates the understanding of various biological processes. To extend the range of function annotation methods to the twilight zone of...
7.
Zhou H, Pandit S, Skolnick J
Proteins . 2009 Jul; 77 Suppl 9:123-7. PMID: 19639638
The performance of the protein structure prediction server pro-sp3-TASSER in CASP8 is described. Compared to CASP7, the major improvement in prediction is in the quality of input models to TASSER....
8.
Zhou H, Pandit S, Lee S, Borreguero J, Chen H, Wroblewska L, et al.
Proteins . 2007 Aug; 69 Suppl 8:90-7. PMID: 17705276
An improved TASSER (Threading/ASSEmbly/Refinement) methodology is applied to predict the tertiary structure for all CASP7 targets. TASSER employs template identification by threading, followed by tertiary structure assembly by rearranging continuous...
9.
Bhadra R, Srinivasan N, Pandit S
In Silico Biol . 2005 Nov; 5(4):379-87. PMID: 16268782
During the course of our large-scale genome analysis a conserved domain, currently detectable only in the genomes of Drosophila melanogaster, Caenorhabditis elegans and Anopheles gambiae, has been identified. The function...
10.
Pandit S, Srinivasan N
In Silico Biol . 2005 Mar; 4(4):563-72. PMID: 15752073
A family of hypothetical proteins, identified predominantly from archaeal genomes, has been analyzed in order to understand its functional characteristics. Using extensive sequence similarity searches it is inferred that this...