Sharon Jancsik
Overview
Explore the profile of Sharon Jancsik including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
492
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0
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Recent Articles
1.
Kruse L, Sunstrum F, Garcia D, Lopez Perez G, Jancsik S, Bohlmann J, et al.
Plant J
. 2023 Nov;
117(3):766-785.
PMID: 37960967
The plant-specialized metabolite montbretin A (MbA) is being developed as a new treatment option for type-2 diabetes, which is among the ten leading causes of premature death and disability worldwide....
2.
Li J, Fernandez K, Ritland C, Jancsik S, Engelhardt D, Coombe L, et al.
BMC Genomics
. 2023 Jul;
24(1):390.
PMID: 37430186
Background: The mountain pine beetle, Dendroctonus ponderosae, is an irruptive bark beetle that causes extensive mortality to many pine species within the forests of western North America. Driven by climate...
3.
Sunstrum F, Liu H, Jancsik S, Madilao L, Bohlmann J, Irmisch S
PLoS One
. 2021 Oct;
16(10):e0257478.
PMID: 34618820
Background: Montbretins are rare specialized metabolites found in montbretia (Crocosmia x crocosmiiflora) corms. Montbretin A (MbA) is of particular interest as a novel therapeutic for type-2 diabetes and obesity. There...
4.
Irmisch S, Jancsik S, Yuen M, Madilao L, Bohlmann J
Plant Physiol
. 2020 Jul;
184(1):97-109.
PMID: 32647038
Diabetes and obesity are affecting human health worldwide. Their occurrence is increasing with lifestyle choices, globalization of food systems, and economic development. The specialized plant metabolite montbretin A (MbA) is...
5.
Booth J, Yuen M, Jancsik S, Madilao L, Page J, Bohlmann J
Plant Physiol
. 2020 Jun;
184(1):130-147.
PMID: 32591428
Cannabis () resin is the foundation of a multibillion dollar medicinal and recreational plant bioproducts industry. Major components of the cannabis resin are the cannabinoids and terpenes. Variations of cannabis...
6.
Irmisch S, Jancsik S, Yuen M, Madilao L, Bohlmann J
Plant J
. 2019 Aug;
100(5):879-891.
PMID: 31400245
Type 2 diabetes (T2D) affects over 320 million people worldwide. Healthy lifestyles, improved drugs and effective nutraceuticals are different components of a response against the growing T2D epidemic. The specialized...
7.
Irmisch S, Ruebsam H, Jancsik S, Yuen M, Madilao L, Bohlmann J
Plant Physiol
. 2019 Apr;
180(3):1277-1290.
PMID: 31004005
The plant metabolite montbretin A (MbA) and its precursor mini-MbA are potential new drugs for treating type 2 diabetes. These complex acylated flavonol glycosides only occur in small amounts in...
8.
Irmisch S, Jo S, Roach C, Jancsik S, Yuen M, Madilao L, et al.
Plant Cell
. 2018 Jul;
30(8):1864-1886.
PMID: 29967287
Plant specialized metabolism serves as a rich resource of biologically active molecules for drug discovery. The acylated flavonol glycoside montbretin A (MbA) and its precursor myricetin 3--(6'--caffeoyl)-glucosyl rhamnoside (mini-MbA) are...
9.
Mageroy M, Jancsik S, Yuen M, Fischer M, Withers S, Paetz C, et al.
Plant Physiol
. 2017 Aug;
175(2):641-651.
PMID: 28794260
Acetophenones are phenolic compounds involved in the resistance of white spruce () against spruce budworm (), a major forest pest in North America. The acetophenones pungenol and piceol commonly accumulate...
10.
Mageroy M, Lachance D, Jancsik S, Parent G, Seguin A, MacKay J, et al.
PeerJ
. 2017 Jul;
5:e3535.
PMID: 28698822
Eastern spruce budworm ( Clemens) (ESBW) is a major forest pest which feeds on young shoots of white spruce () and can cause landscape level economic and ecological losses. Release...