Sharon J Carlson
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Explore the profile of Sharon J Carlson including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
82
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Recent Articles
1.
Carpenter A, Li Y, Miranda I, Wise S, Fatanmi O, Petrus S, et al.
Radiat Res
. 2025 Jan;
203(2):83-95.
PMID: 39786949
BBT-059 is a long-acting PEGylated interleukin-11 analog that has been shown to have hematopoiesis-promoting and anti-apoptotic attributes, and is being studied as a radiation countermeasure for the hematopoietic acute radiation...
2.
Carpenter A, Li Y, Wise S, Fatanmi O, Petrus S, Fam C, et al.
Radiat Res
. 2024 May;
202(1):26-37.
PMID: 38714310
BBT-059, a long-acting PEGylated interleukin-11 (IL-11) analog that is believed to have hematopoietic promoting and anti-apoptotic properties, is being developed as a potential radiation medical countermeasure (MCM) for hematopoietic acute...
3.
Heinzelman P, Carlson S, Cox G
Protein Eng Des Sel
. 2015 Apr;
28(10):461-6.
PMID: 25855658
Crohn's Disease (CD) afflicts over half a million Americans with an annual economic impact exceeding $10 billion. Granulocyte macrophage colony-stimulating factor (GM-CSF) can increase patient immune responses against intestinal microbes...
4.
Fam C, Eisenberg S, Carlson S, Chlipala E, Cox G, Rosendahl M
J Interferon Cytokine Res
. 2014 May;
34(10):759-68.
PMID: 24841172
Interferon gamma (IFN-γ) is a 28 kDa homodimeric cytokine that exhibits potent immunomodulatory, anti-proliferative, and antiviral properties. The protein is used to treat chronic granulomatous disease and malignant osteopetrosis, and...
5.
Cox G, Chlipala E, Smith D, Carlson S, Bell S, Doherty D
PLoS One
. 2014 Mar;
9(3):e91990.
PMID: 24637521
Previously we showed that granulocyte colony-stimulating factor (G-CSF) in vitro bioactivity is preserved when the protein is joined via a flexible 7 amino acid linker to an immunoglobulin-1 (IgG1)-Fc domain...
6.
Bell S, Fam C, Chlipala E, Carlson S, Lee J, Rosendahl M, et al.
Bioconjug Chem
. 2007 Nov;
19(1):299-305.
PMID: 18020402
Recombinant interferon alpha-2 (IFN-alpha2) has proven useful for treating a variety of human cancers and viral diseases. IFN-alpha2 has a short circulating half-life in vivo, which necessitates daily or thrice...
7.
Cox G, Rosendahl M, Chlipala E, Smith D, Carlson S, Doherty D
Endocrinology
. 2007 Jan;
148(4):1590-7.
PMID: 17234711
Recombinant human GH is used to treat GH deficiency in children and adults and wasting in AIDS patients. GH has a circulating half-life of only a few hours in humans...
8.
Rosendahl M, Doherty D, Smith D, Carlson S, Chlipala E, Cox G
Bioconjug Chem
. 2005 Jan;
16(1):200-7.
PMID: 15656592
Recombinant interferon alpha-2 (IFN-alpha2) is used clinically to treat a variety of viral diseases and cancers. IFN-alpha2 has a short circulating half-life, which necessitates frequent administration to patients. Previous studies...
9.
Cox G, Smith D, Carlson S, Bendele A, Chlipala E, Doherty D
Exp Hematol
. 2004 May;
32(5):441-9.
PMID: 15145212
Objective: The aim of this study was to determine whether fusion proteins comprising human granulocyte colony-stimulating factor (G-CSF) joined to human immunoglobulin G1 and G4 (IgG1 and IgG4) Fc and...