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Sharon C A Chen

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Articles 52
Citations 1759
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Recent Articles
1.
Tio S, Chen S, Heath C, Pradhan A, Morris A, Korman T, et al.
Open Forum Infect Dis . 2024 Nov; 11(11):ofae594. PMID: 39494451
Background: International consensus definitions for invasive aspergillosis (IA) in research are rigorous, yet clinically significant cases are often excluded from clinical studies for not meeting proven/probable IA case definitions. To...
2.
Halliday C, Tay E, Green W, Law D, Lopez R, Faris S, et al.
J Antimicrob Chemother . 2024 Aug; 79(10):2611-2621. PMID: 39105545
Background: New antifungal agents are required to mitigate against azole-resistant Aspergillus and drug-resistant non-Aspergillus moulds. The novel orotomide, olorofim (F2G, Manchester, UK), has potent fungicidal activity against Aspergillus including azole-resistant...
3.
Brown L, Rautemaa-Richardson R, Mengoli C, Alanio A, Barnes R, Bretagne S, et al.
Clin Infect Dis . 2024 Jun; 79(1):161-168. PMID: 38860786
Background: This meta-analysis examines the comparative diagnostic performance of polymerase chain reaction (PCR) for the diagnosis of Pneumocystis pneumonia (PCP) on different respiratory tract samples, in both human immunodeficiency virus...
4.
Young J, Andes D, Ardura M, Arrieta A, Bow E, Chandrasekar P, et al.
Open Forum Infect Dis . 2024 Mar; 11(3):ofae082. PMID: 38481428
The epidemiology of invasive aspergillosis (IA) is evolving. To define the patient groups who will most likely benefit from primary or secondary prophylaxis, particularly those whose medical conditions and IA...
5.
Ning Y, Sun T, Dai R, Luo Z, Yu S, Zhang G, et al.
J Antimicrob Chemother . 2023 Nov; 79(1):128-133. PMID: 37991189
Objectives: We explored the epidemiological and molecular characteristics of Candida parapsilosis sensu stricto isolates in China, and their mechanisms of azole resistance. Methods: Azole susceptibilities of 2318 non-duplicate isolates were...
6.
Neoh C, Chen S, Kong D, Hamilton K, Nguyen Q, Spelman T, et al.
J Antimicrob Chemother . 2023 Nov; 79(1):46-54. PMID: 37944018
Background: Little is known about the short- and long-term healthcare costs of invasive Scedosporium/Lomentospora prolificans infections, particularly in patient groups without haematological malignancy. This study investigated excess index hospitalization costs...
7.
Halliday C, Kim H, Tay E, Chen S, Alffenaar J
J Antimicrob Chemother . 2023 Oct; 78(12):2824-2829. PMID: 37823357
Background: Global emergence of rapidly developing resistance to multiple antifungal drugs and high mortality pose challenges to the treatment of invasive Candida auris infections. New therapeutic approaches are needed, such...
8.
Stewart A, Chen S, Hamilton K, Harris-Brown T, Korman T, Figtree M, et al.
Open Forum Infect Dis . 2023 Jun; 10(6):ofad232. PMID: 37274181
Background: infection (CDI) is associated with significant morbidity and mortality in both healthcare and community settings. We aimed to define the predisposing factors, risks for severe disease, and mortality determinants...
9.
Coussement J, Heath C, Roberts M, Lane R, Spelman T, Smibert O, et al.
Clin Infect Dis . 2023 May; 77(7):976-986. PMID: 37235212
Background: Patients without human immunodeficiency virus (HIV) are increasingly recognized as being at risk for cryptococcosis. Knowledge of characteristics of cryptococcosis in these patients remains incomplete. Methods: We conducted a...
10.
Neoh C, Chen S, Crowe A, Hamilton K, Nguyen Q, Marriott D, et al.
Open Forum Infect Dis . 2023 Mar; 10(2):ofad059. PMID: 36861090
Background: Management of infections remains challenging. We described predisposing factors, clinical manifestations, and outcomes of these rare mold infections, including predictors of early (1-month) and late (18-month) all-cause mortality and...