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Shaon Borosha

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Articles 11
Citations 148
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Recent Articles
1.
Chakravarthi V, Dilower I, Ghosh S, Borosha S, Mohamadi R, Dahiya V, et al.
Cells . 2024 Apr; 13(7. PMID: 38607081
Increased activation of ovarian primordial follicles in knockout () rats becomes evident as early as postnatal day 8.5. To identify the ERβ-regulated genes that may control ovarian primordial follicle activation,...
2.
Yu W, Chakravarthi V, Borosha S, Dilower I, Lee E, Ratri A, et al.
Front Cell Dev Biol . 2023 Jan; 10:918235. PMID: 36589740
SATB homeobox proteins are important regulators of developmental gene expression. Among the stem cell lineages that emerge during early embryonic development, trophoblast stem (TS) cells exhibit robust SATB expression. Both...
3.
Feng Y, Borosha S, Ratri A, Lee E, Wang H, Fields T, et al.
Int J Mol Sci . 2022 May; 23(9). PMID: 35563527
Erythropoietin (EPO) signaling plays a vital role in erythropoiesis by regulating proliferation and lineage-specific differentiation of murine hematopoietic progenitor cells (HPCs). An important downstream response of EPO signaling is calcium...
4.
Borosha S, Ratri A, Ghosh S, Malcom C, Chakravarthi V, Vivian J, et al.
Front Genet . 2022 Apr; 13:828086. PMID: 35401699
DOT1L is essential for embryonic hematopoiesis but the precise mechanisms of its action remain unclear. The only recognized function of DOT1L is histone H3 lysine 79 (H3K79) methylation, which has...
5.
Malcom C, Ratri A, Piasecka-Srader J, Borosha S, Chakravarthi V, Alvarez N, et al.
Front Cell Dev Biol . 2022 Feb; 9:813503. PMID: 35111761
DOT1-like (DOT1L) histone methyltransferase is essential for mammalian erythropoiesis. Loss of DOT1L in knockout (KO) mouse embryos resulted in lethal anemia at midgestational age. The only recognized molecular function of...
6.
Chakravarthi V, Ratri A, Masumi S, Borosha S, Ghosh S, Christenson L, et al.
Mol Cell Endocrinol . 2021 Mar; 528:111212. PMID: 33676987
Follicle development beyond the preantral stage is dependent on gonadotropins. FSH signaling is crucial for the advancement of preantral follicles to the antral stage, and LH signaling is essential for...
7.
Khristi V, Ratri A, Ghosh S, Pathak D, Borosha S, Dai E, et al.
Mol Cell Endocrinol . 2019 Apr; 490:47-56. PMID: 30974146
The liver helps maintain energy homeostasis by synthesizing and storing glucose and lipids. Gonadal steroids, particularly estrogens, play an important role in regulating metabolism. As estrogens are considered female hormones,...
8.
Khristi V, Ratri A, Ghosh S, Borosha S, Dai E, Chakravarthi V, et al.
Data Brief . 2019 Jan; 22:771-780. PMID: 30671521
Estrogens are traditionally considered to be female sex steroid hormones and most of the studies examining estrogen regulation of metabolic function in the liver have been conducted in females. However,...
9.
Khristi V, Chakravarthi V, Singh P, Ghosh S, Pramanik A, Ratri A, et al.
Data Brief . 2018 Jun; 19:1008-1011. PMID: 29900397
RNA seq analyses were performed in granulosa cells (GCs) collected from gonadotropin treated ESR2 mutant rats. Data obtained from a null mutant with exon 3 deletion (∆3) and another DNA...
10.
Khristi V, Chakravarthi V, Singh P, Ghosh S, Pramanik A, Ratri A, et al.
Mol Cell Endocrinol . 2018 Mar; 474:214-226. PMID: 29580824
Estrogen receptor 2 (ESR2) plays a critical role in folliculogenesis and ovulation. Disruption of ESR2-function in the rats results in female infertility due to failure of ovulation. Ovulation failure occurred...