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Shannon E Anderson

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Articles 9
Citations 251
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Recent Articles
1.
Turner T, Pittman F, Zhang H, Hymel L, Zheng T, Behara M, et al.
bioRxiv . 2024 Sep; PMID: 39314313
Severe tissue loss resulting from extremity trauma, such as volumetric muscle loss (VML), poses significant clinical challenges for both general and military populations. VML disrupts the endogenous tissue repair mechanisms,...
2.
Kaiser J, Bernard F, Pucha K, Raval S, Eng T, Fulton T, et al.
Osteoarthritis Cartilage . 2024 Apr; 32(7):912-921. PMID: 38642879
Objective: Exercise remains a hallmark treatment for post-traumatic osteoarthritis (PTOA) and may maintain joint homeostasis in part by clearing inflammatory cytokines, cells, and particles. It remains largely unknown whether exercise-induced...
3.
Hymel L, Anderson S, Turner T, York W, Zhang H, Liversage A, et al.
Commun Biol . 2023 Jul; 6(1):749. PMID: 37468760
Volumetric muscle loss (VML) results in permanent functional deficits and remains a substantial regenerative medicine challenge. A coordinated immune response is crucial for timely myofiber regeneration, however the immune response...
4.
Hymel L, Ogle M, Anderson S, San Emeterio C, Turner T, York W, et al.
J Biomed Mater Res A . 2020 Jul; 109(5):695-712. PMID: 32608188
Regeneration of skeletal muscle after volumetric injury is thought to be impaired by a dysregulated immune microenvironment that hinders endogenous repair mechanisms. Such defects result in fatty infiltration, tissue scarring,...
5.
Mohiuddin M, Lee N, Moon J, Han W, Anderson S, Choi J, et al.
Sci Rep . 2019 Jul; 9(1):9551. PMID: 31266969
Critical limb ischemia, the most severe form of peripheral artery disease, leads to extensive damage and alterations to skeletal muscle homeostasis. Although recent research has investigated the tissue-specific responses to...
6.
Han W, Mohiuddin M, Anderson S, Garcia A, Jang Y
Acta Biomater . 2019 Jun; 94:243-252. PMID: 31228633
Skeletal muscle possesses efficient ability to regenerate upon minor injuries, but its capacity to regenerate is severely compromised with traumatic injuries and muscle-associated diseases. Recent evidence suggests that skeletal muscle...
7.
Anderson S, Han W, Srinivasa V, Mohiuddin M, Ruehle M, Moon J, et al.
Tissue Eng Part C Methods . 2019 Jan; 25(2):59-70. PMID: 30648479
The goal of this study was to determine the threshold for a critically sized, nonhealing muscle defect by characterizing key components in the balance between fibrosis and regeneration as a...
8.
Sago C, Lokugamage M, Paunovska K, Vanover D, Monaco C, Shah N, et al.
Proc Natl Acad Sci U S A . 2018 Oct; 115(42):E9944-E9952. PMID: 30275336
Dysfunctional endothelium causes more disease than any other cell type. Systemically administered RNA delivery to nonliver tissues remains challenging, in large part because there is no high-throughput method to identify...
9.
Han W, Anderson S, Mohiuddin M, Barros D, Nakhai S, Shin E, et al.
Sci Adv . 2018 Aug; 4(8):eaar4008. PMID: 30116776
Muscle satellite cells (MuSCs) play a central role in muscle regeneration, but their quantity and function decline with comorbidity of trauma, aging, and muscle diseases. Although transplantation of MuSCs in...