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Shangqin Chen

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Articles 32
Citations 232
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Recent Articles
1.
Zhu M, Lin J, Zhuge Z, Zheng Y, Ye S, Wang X, et al.
Infect Drug Resist . 2024 Dec; 17:5277-5286. PMID: 39619726
Purpose: Neonatal bacterial meningitis (NBM) is a serious disease with high morbidity and mortality. This study aimed to establish a foundation for the selection of empirical antibiotics for NBM through...
2.
Hu X, Zheng Y, Fang M, Liang Z, Wen C, Lin J, et al.
Respir Res . 2024 Nov; 25(1):412. PMID: 39568008
Background: Abnormal pulmonary vascular development poses significant clinical challenges for infants with bronchopulmonary dysplasia (BPD). Although numerous factors have been suggested to control the development of pulmonary blood vessels, the...
3.
Lu L, Pang M, Chen T, Hu Y, Chen L, Tao X, et al.
Drug Des Devel Ther . 2024 Nov; 18:4975-4992. PMID: 39525050
Introduction: Neonatal hypoxic-ischemic encephalopathy (HIE), caused by perinatal asphyxia, is characterized by high morbidity and mortality, but there are still no effective therapeutic drugs. Mitochondrial biogenesis and apoptosis play key...
4.
Hu Y, Nan Y, Lin H, Zhao Q, Chen T, Tao X, et al.
Pediatr Res . 2024 May; 96(7):1681-1692. PMID: 38763946
Background: Hypoxic-ischemic encephalopathy (HIE) is caused by perinatal hypoxia and subsequent reductions in cerebral blood flow and is one of the leading causes of severe disability or death in newborns....
5.
Wen C, Chen H, Tang Y, Lin H, Xu C, Ying Y, et al.
Ecotoxicol Environ Saf . 2024 Mar; 273:116173. PMID: 38452703
Per- and polyfluoroalkyl (PFAS) substances are enduring industrial materials. 17β-Hydroxysteroid dehydrogenase isoform 1 (17β-HSD1) is an estrogen metabolizing enzyme, which transforms estrone into estradiol in human placenta and rat ovary....
6.
Huang Y, Zhang J, You D, Chen S, Lin Z, Li B, et al.
Comp Biochem Physiol C Toxicol Pharmacol . 2023 Dec; 276:109813. PMID: 38070757
The globally prevalent of sleep disorders is partly attributed to unhealthy dietary habits. This study investigated the underlying mechanisms of elevated palmitic acid (PA) intake on locomotor activity and sleep...
7.
Chen T, Hu Y, Lu L, Zhao Q, Tao X, Ding B, et al.
Front Pharmacol . 2023 Mar; 14:1134464. PMID: 36969871
Hypoxic-ischemic encephalopathy (HIE) is a crucial cause of neonatal death and neurological sequelae, but currently there is no effective therapy drug for HIE. Both oxidative stress and apoptosis play critical...
8.
Shi J, Chen S, Lu A, Liang Y, Wang Q, Lu C, et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi . 2023 Jan; 40(2):234-237. PMID: 36709948
Objective: To explore the genetic basis for a child with facial dysmorphism and multiple malformations. Methods: The child, born at 34 weeks' gestation due to premature rupture of amniotic membrane,...
9.
Pan S, Lin S, Lin J, Chen S, Lin Z
Ital J Pediatr . 2022 Jun; 48(1):99. PMID: 35710574
Background: Brain abscesses are uncommon but life-threatening in extremely preterm (EP, Gestational Age < 28 weeks) infants. The information of long-time follow-up is rare, but very few cases presented almost...
10.
Wang X, Huo R, Liang Z, Xu C, Chen T, Lin J, et al.
Oxid Med Cell Longev . 2022 May; 2022:8336070. PMID: 35509841
Bronchopulmonary dysplasia (BPD) is a chronic lung disease commonly found in premature infants. Excessive inflammation and oxidative stress contribute to BPD occurrence and development. Simvastatin, as an inhibitor of HMG-CoA...