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Shanequa Manuel

Explore the profile of Shanequa Manuel including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 142
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Recent Articles
1.
Advani S, Shi Q, Overman M, Loree J, Lam M, Morris V, et al.
Clin Colorectal Cancer . 2020 Feb; 19(1):48-56.e2. PMID: 32008976
Background: The survival of patients with metastatic colorectal cancer (mCRC) is influenced by the genetic and epigenetic changes that might influence the patient experience of symptom burden. Understanding the association...
2.
Pereira A, Morelli M, Overman M, Kee B, Fogelman D, Vilar E, et al.
PLoS One . 2017 Aug; 12(8):e0183949. PMID: 28850629
Background: Circulating cell-free DNA (cfDNA) isolated from the plasma of cancer patients (pts) has been shown to reflect the genomic mutation profile of the tumor. However, physician and patient assessment...
3.
Katsiampoura A, Raghav K, Jiang Z, Menter D, Varkaris A, Morelli M, et al.
Mol Cancer Ther . 2017 May; 16(7):1435-1442. PMID: 28468778
Developing realistic preclinical models using clinical samples that mirror complex tumor biology and behavior are vital to advancing cancer research. While cell line cultures have been helpful in generating preclinical...
4.
Korphaisarn K, Morris V, Overman M, Fogelman D, Kee B, Raghav K, et al.
Oncotarget . 2017 Apr; 8(24):39268-39279. PMID: 28424412
Background: FBXW7 functions as a ubiquitin ligase tagging multiple dominant oncogenic proteins and commonly mutates in colorectal cancer. Data suggest missense mutations lead to greater loss of FBXW7 function than...
5.
Mehrvarz Sarshekeh A, Advani S, Overman M, Manyam G, Kee B, Fogelman D, et al.
PLoS One . 2017 Mar; 12(3):e0173345. PMID: 28267766
SMAD4 is an essential mediator in the transforming growth factor-β pathway. Sporadic mutations of SMAD4 are present in 2.1-20.0% of colorectal cancers (CRCs) but data are limited. In this study,...