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Shane Shapera

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Citations 559
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Recent Articles
1.
Marinescu D, Hague C, Muller N, Murphy D, Churg A, Wright J, et al.
Radiology . 2025 Feb; 314(2):e241001. PMID: 39903073
Background Prognostic value of radiologic features in interstitial lung disease (ILD) has been predominantly studied in idiopathic pulmonary fibrosis, but findings vary. The relative importance of features versus guideline-defined patterns...
2.
Kreuter M, Belloli E, Bendstrup E, Cerri S, Flaherty K, Shapera S, et al.
ERJ Open Res . 2024 Dec; 10(6). PMID: 39624387
Background: Acute exacerbations of fibrosing interstitial lung diseases (ILDs) are associated with high mortality. We used prospective data from the INBUILD trial to investigate risk factors for acute exacerbations and...
3.
Cheema P, Iafolla M, Abdel-Qadir H, Bellini A, Chatur N, Chandok N, et al.
Curr Oncol . 2024 Oct; 31(10):6356-6383. PMID: 39451777
The increased use of immune checkpoint inhibitors (ICIs) across cancer programs has created the need for standardized monitoring and management of immune-related adverse events (irAEs). Delayed recognition without appropriate treatment...
4.
Grant-Orser A, Asmussen M, Marinescu D, Hague C, Muller N, Murphy D, et al.
Chest . 2024 Aug; 167(1):172-182. PMID: 39179174
Background: BAL cellular analysis is often recommended during the initial diagnostic evaluation of fibrotic interstitial lung disease (ILD). Despite recommendation for its use, between-center heterogeneity exists and supportive data concerning...
5.
Wu J, Xu J, Vasileva A, Nohra C, Binnie M, Shapera S, et al.
Respir Med Case Rep . 2024 Apr; 49:102016. PMID: 38559325
Oscillometry is an emerging pulmonary function testing tool that is conducted during tidal breaths with minimal patient effort. It is highly sensitive to changes in lung mechanics. Oscillometry was recently...
6.
Van Hollebeke M, Chohan K, Adams C, Fisher J, Shapera S, Fidler L, et al.
Chron Respir Dis . 2024 Mar; 21:14799731241240786. PMID: 38515270
Background: Approximately 50% of patients with interstitial lung disease (ILD) experience frailty, which remains unexplored in acute exacerbations of ILD (AE-ILD). A better understanding may help with prognostication and resource...
7.
Marcoux V, Lok S, Mondal P, Assayag D, Fisher J, Shapera S, et al.
Respirology . 2024 Mar; 29(7):596-604. PMID: 38436522
Background And Objective: Establishing an accurate and timely diagnosis of idiopathic pulmonary fibrosis (IPF) is essential for appropriate management and prognostication. In some cases, surgical lung biopsy (SLB) is performed...
8.
Guler S, Marinescu D, Cox G, Durand C, Fisher J, Grant-Orser A, et al.
Chest . 2024 Feb; 166(3):517-527. PMID: 38423280
Background: Previous studies have shown the importance of frailty in patients with fibrotic interstitial lung disease (ILD). Research Question: Is the Clinical Frailty Scale (CFS) a valid tool to improve...
9.
Zheng B, Marinescu D, Hague C, Muller N, Murphy D, Churg A, et al.
Rheumatology (Oxford) . 2024 Feb; 63(10):2734-2740. PMID: 38336872
Objectives: Interstitial lung disease (ILD) in CTDs has highly variable morphology. We aimed to identify imaging features and their impact on ILD progression, mortality, and immunosuppression response. Methods: Patients with...
10.
Wee W, Shapera S, To T, Chiu P, Dell S, Fisher J
Ann Am Thorac Soc . 2024 Jan; 21(5):767-773. PMID: 38261360
Surgical lung biopsies are often required for the definitive diagnosis of nonmalignant pediatric diffuse lung diseases; however, the literature on mortality after surgical lung biopsy in pediatric patients is sparse....