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Shane D Wainwright

Explore the profile of Shane D Wainwright including associated specialties, affiliations and a list of published articles. Areas
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Citations 298
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Recent Articles
1.
Langdon-Jones E, Lloyd D, Hayes A, Wainwright S, Mottram H, Coles S, et al.
Inorg Chem . 2015 Jun; 54(13):6606-15. PMID: 26086352
A range of fluorescent alkynyl-naphthalimide fluorophores has been synthesized and their photophysical properties examined. The fluorescent ligands are based upon a 4-substituted 1,8-naphthalimide core and incorporate structural variations (at the...
2.
Wainwright S, Bondeson J, Caterson B, Hughes C
Arthritis Rheum . 2013 Jul; 65(11):2866-75. PMID: 23897278
Objective: We previously described a messenger RNA variant of ADAMTS4 (ADAMTS4_v1) in human synovial cell cocultures obtained from patients with osteoarthritis (OA). This RNA message has been found only in...
3.
Bondeson J, Wainwright S, Lauder S, Amos N, Hughes C
Arthritis Res Ther . 2006 Dec; 8(6):R187. PMID: 17177994
There is an increasing body of evidence that synovitis plays a role in the progression of osteoarthritis and that overproduction of cytokines and growth factors from the inflamed synovium can...
4.
Jones A, Gleghorn J, Hughes C, Fitz L, Zollner R, Wainwright S, et al.
J Orthop Res . 2006 Nov; 25(3):283-92. PMID: 17106881
Lubricin is a secreted, cytoprotective glycoprotein that contributes to the essential boundary lubrication mechanisms necessary for maintaining low friction levels at articular cartilage surfaces. Diminishment of lubricin function is thereby...
5.
Wainwright S, Bondeson J, Hughes C
Matrix Biol . 2006 May; 25(5):317-20. PMID: 16723216
The major proteoglycan of articular cartilage aggrecan is a substrate for ADAMTS4. RT-PCR analysis of human osteoarthritic (OA) synovial co-cultures using oligonucleotide primers designed to amplify across the exon 8/9...