Shan H Shao
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Explore the profile of Shan H Shao including associated specialties, affiliations and a list of published articles.
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8
Citations
559
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Recent Articles
1.
Shetty G, Porter K, Zhou W, Shao S, Weng C, Meistrich M
Endocrinology
. 2011 Jul;
152(9):3504-14.
PMID: 21733828
Why both testosterone (T) suppression and cryptorchidism reverse the block in spermatogonial differentiation in adult mice homozygous for the juvenile spermatogonial depletion (jsd) mutation has been a conundrum. To resolve...
2.
Zhou W, Bolden-Tiller O, Shao S, Weng C, Shetty G, Abuelhija M, et al.
Biol Reprod
. 2011 Jun;
85(4):823-33.
PMID: 21653891
Despite numerous observations of the effects of estrogens on spermatogenesis, identification of estrogen-regulated genes in the testis is limited. Using rats in which irradiation had completely blocked spermatogonial differentiation, we...
3.
Wang G, Shao S, Weng C, Wei C, Meistrich M
Toxicol Sci
. 2010 Jun;
117(1):225-37.
PMID: 20584762
Irradiation interrupts spermatogenesis and causes prolonged sterility in male mammals. Hormonal suppression treatment with gonadotropin-releasing hormone (GnRH) analogues has restored spermatogenesis in irradiated rats, but similar attempts were unsuccessful in...
4.
Zhou W, Bolden-Tiller O, Shetty G, Shao S, Weng C, Pakarinen P, et al.
Biol Reprod
. 2009 Aug;
82(1):54-65.
PMID: 19684331
Although gonadotropins and androgen are required for normal spermatogenesis and both testosterone and follicle-stimulating hormone (FSH) are responsible for the inhibition of spermatogonial differentiation that occurs in irradiated rats, it...
5.
Wang G, Weng C, Shao S, Zhou W, De Gendt K, Braun R, et al.
J Androl
. 2009 Jan;
30(3):338-48.
PMID: 19136388
Testosterone acting through the androgen receptor (AR) maintains the arrest of spermatogonial differentiation in juvenile spermatogonial depletion (jsd mutation in the Utp14b gene) mutant adult male mice. It is not...
6.
Larrea M, Liang J, da Silva T, Hong F, Shao S, Han K, et al.
Mol Cell Biol
. 2008 Aug;
28(20):6462-72.
PMID: 18710949
p27 mediates Cdk2 inhibition and is also found in cyclin D1-Cdk4 complexes. The present data support a role for p27 in the assembly of D-type cyclin-Cdk complexes and indicate that...
7.
Shetty G, Shao S, Weng C
Endocrinology
. 2008 Mar;
149(6):2773-81.
PMID: 18356279
In adult male mice homozygous for the juvenile spermatogonial depletion (Utp14b jsd) mutation in the Utp14b gene, type A spermatogonia proliferate, but in the presence of testosterone and at scrotal...
8.
Liang J, Shao S, Xu Z, Hennessy B, Ding Z, Larrea M, et al.
Nat Cell Biol
. 2007 Jan;
9(2):218-24.
PMID: 17237771
Nutrients and bioenergetics are prerequisites for proliferation and survival of mammalian cells. We present evidence that the cyclin-dependent kinase inhibitor p27(Kip1), is phosphorylated at Thr 198 downstream of the Peutz-Jeghers...