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Shamseldin Metwally

Explore the profile of Shamseldin Metwally including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Collier J, Metwally S, McFarland M, Krishna S, Kurella P, Fiesler V, et al.
Aging Dis . 2025 Feb; PMID: 39965246
Reactive astrogliosis has been indicated as one of the earliest pathological biomarkers in Alzheimer's Disease (AD) pathology. We previously reported that upregulation of the Na/H exchanger isoform 1 (NHE1) protein...
2.
Metwally S, Capuk O, Wang J, Bhuiyan M, Li Q, Kaliyappan K, et al.
Neurochem Int . 2025 Feb; 184:105939. PMID: 39909157
Background: Recent evidence suggests extra-cortical adaptations within the cerebellum may contribute to motor recovery in patients with cortical ischemic strokes. The molecular/cellular adaptations enabling this effect to have not been...
3.
Lin L, Chen Y, He K, Metwally S, Jha R, Capuk O, et al.
J Neuroinflammation . 2024 Sep; 21(1):220. PMID: 39256783
Background: The choroid plexus (ChP) helps maintain the homeostasis of the brain by forming the blood-CSF barrier via tight junctions (TJ) at the choroid plexus epithelial cells, and subsequently preventing...
4.
Song S, Oft H, Metwally S, Paruchuri S, Bielanin J, Fiesler V, et al.
J Neuroinflammation . 2024 Mar; 21(1):69. PMID: 38509618
Microglial Na/H exchanger-1 (NHE1) protein, encoded by Slc9a1, plays a role in white matter demyelination of ischemic stroke brains. To explore underlying mechanisms, we conducted single cell RNA-seq transcriptome analysis...
5.
Song S, Hasan M, Yu L, Paruchuri S, Bielanin J, Metwally S, et al.
J Neuroinflammation . 2022 Oct; 19(1):246. PMID: 36199097
Differential microglial inflammatory responses play a role in regulation of differentiation and maturation of oligodendrocytes (OLs) in brain white matter. How microglia-OL crosstalk is altered by traumatic brain injury (TBI)...