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» Authors » Shalmali Bivalkar-Mehla

Shalmali Bivalkar-Mehla

Explore the profile of Shalmali Bivalkar-Mehla including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 276
Followers 0
Related Specialties
General Medicine
Science
Biochemistry
Top 10 Co-Authors
Ashok Chauhan
Rajeev Mehla
Mitzi Nagarkatti
Eileen Martin
Janaki Vakharia
Ann Ragin
Velpandi Ayyavoo
Deepika Puri
Indhira Handy
Deepa Subramanyam
Published In
PLoS One
J Drug Target
Virus Res
AIDS
J Neuroinflammation
Affiliations
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Recent Articles
1.
Understanding the role of Beclin1 in mouse embryonic stem cell differentiation through CRISPR-Cas9-mediated gene editing
Bivalkar-Mehla S, Puri D, Singh S, Subramanyam D
J Biosci . 2021 Mar; 46. PMID: 33737502
Autophagy is a vacuolar pathway for the regulated degradation and recycling of cellular components. Beclin1, a Bcl2-interacting protein, is a well-studied autophagy regulator. Homozygous loss of Beclin1 in mice leads...
2.
Transcriptome analyses identify key cellular factors associated with HIV-1-associated neuropathogenesis in infected men
Venkatachari N, Jain S, Walker L, Bivalkar-Mehla S, Chattopadhyay A, Bar-Joseph Z, et al.
AIDS . 2016 Dec; 31(5):623-633. PMID: 28005686
Objective: HIV-1 viral proteins and host inflammatory factors have a direct role in neuronal toxicity in vitro; however, the contribution of these factors in vivo in HIV-1-associated neurocognitive disorder (HAND)...
3.
Chimeric peptide-mediated siRNA transduction to inhibit HIV-1 infection
Bivalkar-Mehla S, Mehla R, Chauhan A
J Drug Target . 2016 Nov; 25(4):307-319. PMID: 27800697
Persistent human immunodeficiency virus 1 (HIV-1) infection provokes immune activation and depletes CD4lymphocytes, leading to acquired immunodeficiency syndrome. Uninterrupted administration of combination antiretroviral therapy (cART) in HIV-infected patients suppresses viral...
4.
Programming of neurotoxic cofactor CXCL-10 in HIV-1-associated dementia: abrogation of CXCL-10-induced neuro-glial toxicity in vitro by PKC activator
Mehla R, Bivalkar-Mehla S, Nagarkatti M, Chauhan A
J Neuroinflammation . 2012 Oct; 9:239. PMID: 23078780
Background: More than 50% of patients undergoing lifelong suppressive antiviral treatment for HIV-1 infection develop minor HIV-1-associated neurocognitive disorders. Neurological complications during HIV-1 infection are the result of direct neuronal...
5.
A flavonoid, luteolin, cripples HIV-1 by abrogation of tat function
Mehla R, Bivalkar-Mehla S, Chauhan A
PLoS One . 2011 Dec; 6(11):e27915. PMID: 22140483
Despite the effectiveness of combination antiretroviral treatment (cART) against HIV-1, evidence indicates that residual infection persists in different cell types. Intensification of cART does not decrease the residual viral load...
6.
Viral RNA silencing suppressors (RSS): novel strategy of viruses to ablate the host RNA interference (RNAi) defense system
Bivalkar-Mehla S, Vakharia J, Mehla R, Abreha M, Kanwar J, Tikoo A, et al.
Virus Res . 2010 Oct; 155(1):1-9. PMID: 20951748
Pathogenic viruses have developed a molecular defense arsenal for their survival by counteracting the host anti-viral system known as RNA interference (RNAi). Cellular RNAi, in addition to regulating gene expression...
7.
Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner
Mehla R, Bivalkar-Mehla S, Zhang R, Handy I, Albrecht H, Giri S, et al.
PLoS One . 2010 Jun; 5(6):e11160. PMID: 20585398
HIV's ability to establish long-lived latent infection is mainly due to transcriptional silencing in resting memory T lymphocytes and other non dividing cells including monocytes. Despite an undetectable viral load...