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Shalini Saggu

Explore the profile of Shalini Saggu including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 271
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Recent Articles
1.
Saggu S, Srivastava R, McCormick L, Agarwal A, Khan M, Athar M
Chemosphere . 2024 Oct; 367:143516. PMID: 39389373
Unused warfare chemical agents, developed in World Wars I/II dumped in the ocean or buried at various sites across the world, pose significant environmental and human health risks. This review...
2.
Saggu S, Bai A, Aida M, Rehman H, Pless A, Ware D, et al.
Geroscience . 2024 Sep; 47(1):457-482. PMID: 39331291
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by relentless cognitive decline and the emergence of profoundly disruptive neuropsychiatric symptoms. As the disease progresses, it unveils a formidable array...
3.
Zhang C, Aida M, Saggu S, Yu H, Zhou L, Rehman H, et al.
Sci Adv . 2024 Jun; 10(25):eadn8709. PMID: 38905345
Androgen deprivation therapy (ADT) for prostate cancer is associated with an increased risk of dementia, including Alzheimer's disease (AD). The mechanistic connection between ADT and AD-related cognitive impairment in patients...
4.
Pless A, Ware D, Saggu S, Rehman H, Morgan J, Wang Q
Front Neurosci . 2023 Sep; 17:1263771. PMID: 37732300
Neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) affect up to 97% of AD patients, with an estimated 80% of current AD patients experiencing these symptoms. Common AD-associated NPS include depression,...
5.
Saggu S, Chen Y, Cottingham C, Rehman H, Wang H, Zhang S, et al.
Mol Psychiatry . 2022 Nov; 28(2):588-600. PMID: 36357671
Posttraumatic stress disorder (PTSD) after the pandemic has emerged as a major neuropsychiatric component of post-acute COVID-19 syndrome, yet the current pharmacotherapy for PTSD is limited. The use of adrenergic...
6.
Saggu S, Chen Y, Chen L, Pizarro D, Pati S, Law W, et al.
JCI Insight . 2022 Jun; 7(11). PMID: 35674133
Epileptic seizures are common sequelae of stroke, acute brain injury, and chronic neurodegenerative diseases, including Alzheimer's disease (AD), and cannot be effectively controlled in approximately 40% of patients, necessitating the...
7.
Saggu S, Rehman H, Aziz A, Alzeibr F, Oyouni A, Zidan N, et al.
Saudi J Biol Sci . 2019 Nov; 26(7):1875-1881. PMID: 31762670
Cadmium is among the toxic and hazardous metal widely dispersed in the environment in high levels. Current studies have provided new insights into antioxidant properties of bioflavonoid which have emerged...
8.
Hawsawi Y, Al-Zahrani F, Mavromatis C, Baghdadi M, Saggu S, Oyouni A
Technol Cancer Res Treat . 2018 Oct; 17:1533033818806910. PMID: 30343639
Since the original discovery of stem cells, a new era of promising results has emerged in the clinical application of stem cells for the treatment of several important diseases, including...
9.
Oyouni A, Saggu S, Tousson E, Rehman H
Toxicol Rep . 2018 Jul; 5:687-694. PMID: 30003047
Tacrolimus (TAC) is used sporadically as an immunosuppressive agent for organ transplantation, but its clinical used is limited due to its marked nephrotoxicity. L. (Lamiaceae) (OB) had been shown to...
10.
Abbas Z, Saggu S, Rehman H, Al Thbiani A, Ansari A
Saudi J Biol Sci . 2017 Sep; 24(6):1268-1273. PMID: 28855821
L. (Compositae) are shrubby herbs growing wildly in Tabuk region and distributed in the desert regions. This region is characterized by extremely variable environmental conditions where the temperature varies from...